ID A0A1X1QGX1_9GAMM Unreviewed; 567 AA.
AC A0A1X1QGX1;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=A6F71_05695 {ECO:0000313|EMBL:ORU90458.1};
OS Cycloclasticus sp. symbiont of Poecilosclerida sp. M.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Cycloclasticus.
OX NCBI_TaxID=1840537 {ECO:0000313|EMBL:ORU90458.1, ECO:0000313|Proteomes:UP000193579};
RN [1] {ECO:0000313|EMBL:ORU90458.1, ECO:0000313|Proteomes:UP000193579}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Specimen M {ECO:0000313|EMBL:ORU90458.1};
RA Rubin Blum M., Dubilier N.;
RT "Short-chain alkanes fuel the metabolism of mussel and sponge
RT Cycloclasticus symbionts from deep-sea gas and oil seeps.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORU90458.1}.
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DR EMBL; LWTN01000220; ORU90458.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X1QGX1; -.
DR STRING; 1840537.A6F71_05695; -.
DR Proteomes; UP000193579; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00143; PP2Cc; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR24346; MAP/MICROTUBULE AFFINITY-REGULATING KINASE; 1.
DR PANTHER; PTHR24346:SF30; MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13672; PP2C_2; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51746; PPM_2; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ORU90458.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000193579};
KW Transferase {ECO:0000313|EMBL:ORU90458.1}.
FT DOMAIN 8..236
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT DOMAIN 269..526
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 567 AA; 64292 MW; 81731702B820DBAF CRC64;
MQANSLIDLG QYSDKGVKEE NQDSYGMLLP ESPVLEQKGI SIVIADGVSG CDHGKLASES
CVKSLLSDYY CTPDSWTVKT SVQKVLLATN RWMLGMAQQG GDHYKGLATT MSALIVKSST
VHLFHIGDTR IYRIRNKKLE LLTKDHRFWV SKDKNYLTRA MGIDLHLDID YSNFLLEEGD
AFLLTTDGVH EFVSDAVMLN RVVDNANNLD RAAREITALA MQKGSDDNVT CQIVRFNQLP
QINDDEVYRK LAELPFPPDL NAGMILDGYR IERELHASKR TQVYLATDEE TGSKVVIKTP
SVNFADDPSY LDMFVHEEWV GRRVDNNHVV KIVEQTRPRT FLYYVTEYVE GQTLRHWMSD
NPQPSMHEVR GIVRQIARGL RAFHRKEMIH QDLKPENIII DTNETVKIID FGSTKVAGVE
EISTPVHRLS LLGTQHYTAP EYILGQPASY LSDAFSLGVI TYEMLTGHLP FGEKYGEKAL
SKLKYTSALD FNSDIPLWVD GAIRKIVKRK PSNRYEEISE YVHDLSYANK LFTETKHVPL
IERNPAIFWK NVALLSLIGN IALAIFK
//
