ID   A0A1X1QNP6_9GAMM        Unreviewed;       391 AA.
AC   A0A1X1QNP6;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=tryptophan--tRNA ligase {ECO:0000256|ARBA:ARBA00013161};
DE            EC=6.1.1.2 {ECO:0000256|ARBA:ARBA00013161};
GN   ORFNames=A6F72_05560 {ECO:0000313|EMBL:ORU92825.1};
OS   Cycloclasticus sp. symbiont of Poecilosclerida sp. N.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC   Piscirickettsiaceae; Cycloclasticus.
OX   NCBI_TaxID=1840472 {ECO:0000313|EMBL:ORU92825.1, ECO:0000313|Proteomes:UP000193416};
RN   [1] {ECO:0000313|EMBL:ORU92825.1, ECO:0000313|Proteomes:UP000193416}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Specimen N {ECO:0000313|EMBL:ORU92825.1};
RA   Rubin Blum M., Dubilier N.;
RT   "Short-chain alkanes fuel the metabolism of mussel and sponge
RT   Cycloclasticus symbionts from deep-sea gas and oil seeps.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|ARBA:ARBA00005594, ECO:0000256|RuleBase:RU363036}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORU92825.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LWTM01000071; ORU92825.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X1QNP6; -.
DR   STRING; 1840472.A6F72_05560; -.
DR   Proteomes; UP000193416; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004830; F:tryptophan-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006436; P:tryptophanyl-tRNA aminoacylation; IEA:InterPro.
DR   CDD; cd00806; TrpRS_core; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   Gene3D; 1.10.240.10; Tyrosyl-Transfer RNA Synthetase; 1.
DR   InterPro; IPR001412; aa-tRNA-synth_I_CS.
DR   InterPro; IPR002305; aa-tRNA-synth_Ic.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR002306; Trp-tRNA-ligase.
DR   NCBIfam; TIGR00233; trpS; 1.
DR   PANTHER; PTHR43766; TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43766:SF1; TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL; 1.
DR   Pfam; PF00579; tRNA-synt_1b; 2.
DR   PRINTS; PR01039; TRNASYNTHTRP.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR   PROSITE; PS00178; AA_TRNA_LIGASE_I; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW   ECO:0000256|RuleBase:RU363036};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363036};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363036};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU363036};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW   ECO:0000256|RuleBase:RU363036};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193416}.
SQ   SEQUENCE   391 AA;  44117 MW;  FCA28FD0191D0831 CRC64;
     MRPTGNLHLG HYHGVLKNWL ELQQEYKCYF FVADWHALTT HYDNPSIIAD STLNMVIDWL
     AAGVDHGLAD LFIQSSIPEH AELHLLLSMM TPLGWLERVP SYKDQQERLK EKDLATYGFL
     GYPLLQSADI LMYKAGLVPV GADQVAHVEL TREVARRFNH LYGGEPDFEE KAEIAIKKMG
     KKNAKMFNKL RNAYQENGDQ EALAVARALL EAQQNITVGD KERLFGYLEG SGRVILPEPK
     ALLTKASKMP GLDGQKMSKS YGNTIALRDK VEDVEKKLRT MPTDPARVRL TDVGDPAKCP
     VWQFHEVYSN EEVCEWVQNG CKTACIGCLD CKAPVIEAVL RELKPMQERA AEYTQQPDLV
     RSIINEGTEK ARDVAKETLD EVKEAMSMKL L
//