ID A0A1X1QPW7_9GAMM Unreviewed; 314 AA.
AC A0A1X1QPW7;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Radical SAM protein {ECO:0000313|EMBL:ORU93104.1};
GN ORFNames=A6F70_04805 {ECO:0000313|EMBL:ORU93104.1};
OS Cycloclasticus sp. symbiont of Bathymodiolus heckerae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Cycloclasticus.
OX NCBI_TaxID=1284675 {ECO:0000313|EMBL:ORU93104.1, ECO:0000313|Proteomes:UP000193616};
RN [1] {ECO:0000313|EMBL:ORU93104.1, ECO:0000313|Proteomes:UP000193616}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Specimen P {ECO:0000313|EMBL:ORU93104.1};
RA Rubin Blum M., Dubilier N.;
RT "Short-chain alkanes fuel the metabolism of mussel and sponge
RT Cycloclasticus symbionts from deep-sea gas and oil seeps.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORU93104.1}.
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DR EMBL; LWTL01000117; ORU93104.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X1QPW7; -.
DR STRING; 1284675.A6F70_04805; -.
DR Proteomes; UP000193616; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR024521; ArsS-like_C.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR026351; rSAM_ArsS-like.
DR NCBIfam; TIGR04167; rSAM_SeCys; 1.
DR PANTHER; PTHR43728:SF1; RADICAL SAM SUPERFAMILY PROTEIN-RELATED; 1.
DR PANTHER; PTHR43728; SLR0304 PROTEIN; 1.
DR Pfam; PF12345; DUF3641; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000193616};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 27..163
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|Pfam:PF04055"
FT DOMAIN 179..312
FT /note="Arsenosugar biosynthesis radical SAM protein ArsS-
FT like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12345"
SQ SEQUENCE 314 AA; 34820 MW; 6B5605BC7615923F CRC64;
MHSTLEKLAL TDFPSINRHA LDTLQVNLGY LCNLSCLHCH VNAGPTRKEL MNKQTIDTLL
LFIDKHNIKT LDLTGGAPEM NPHFEYIVLE AVKREVTVID RCNLTILEEH GYEHMAEFMA
SNGVQIVASL PCYSSDNVDA QRGNGVFDKS ISALQTLNRL GYGKTLQLDL VFNPQGAQLP
PNQATLELEY KTHLRENFGI EFSQLLTITN MPIKRFGSTL VSKGQFTNYM DMLKSAYQAV
NLNNLMCKSL LSVDWEGYDC DFNQMLELSA GFSGSKKHIS NCMDVSFNQQ PITIADHCYG
CTAGSGSSCG GSLT
//
