ID A0A1X1RHT2_MYCFA Unreviewed; 670 AA.
AC A0A1X1RHT2;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Helicase {ECO:0000313|EMBL:BBY96581.1, ECO:0000313|EMBL:ORV06638.1};
GN ORFNames=AWC04_04035 {ECO:0000313|EMBL:ORV06638.1}, MFAL_00480
GN {ECO:0000313|EMBL:BBY96581.1};
OS Mycolicibacterium fallax (Mycobacterium fallax).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1793 {ECO:0000313|EMBL:ORV06638.1, ECO:0000313|Proteomes:UP000193484};
RN [1] {ECO:0000313|EMBL:ORV06638.1, ECO:0000313|Proteomes:UP000193484}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44179 {ECO:0000313|EMBL:ORV06638.1,
RC ECO:0000313|Proteomes:UP000193484};
RA Tarcisio F., Conor M., Antonella G., Elisabetta G., Giulia F.S., Sara T.,
RA Anna F., Clotilde B., Roberto B., Veronica D.S., Fabio R., Monica P.,
RA Olivier J., Enrico T., Nicola S.;
RT "The new phylogeny of the genus Mycobacterium.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BBY96581.1, ECO:0000313|Proteomes:UP000467101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 6405 {ECO:0000313|EMBL:BBY96581.1,
RC ECO:0000313|Proteomes:UP000467101};
RX PubMed=31287781;
RA Matsumoto Y., Kinjo T., Motooka D., Nabeya D., Jung N., Uechi K., Horii T.,
RA Iida T., Fujita J., Nakamura S.;
RT "Comprehensive subspecies identification of 175 nontuberculous mycobacteria
RT species based on 7547 genomic profiles.";
RL Emerg. Microbes Infect. 8:1043-1053(2019).
RN [3] {ECO:0000313|EMBL:BBY96581.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 6405 {ECO:0000313|EMBL:BBY96581.1};
RA Matsumoto Y., Motooka D., Nakamura S.;
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. DinG subfamily.
CC {ECO:0000256|ARBA:ARBA00038058}.
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DR EMBL; AP022603; BBY96581.1; -; Genomic_DNA.
DR EMBL; LQOJ01000020; ORV06638.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X1RHT2; -.
DR STRING; 1793.AWC04_04035; -.
DR KEGG; mfx:MFAL_00480; -.
DR OrthoDB; 9805194at2; -.
DR Proteomes; UP000193484; Unassembled WGS sequence.
DR Proteomes; UP000467101; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:ORV06638.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000193484}.
FT DOMAIN 11..312
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
SQ SEQUENCE 670 AA; 70671 MW; AE6BCA2B8F8ABB0D CRC64;
MADTSVTELL AAAVTALGGT RRDGQVAMAE AVDRAFHTGE HLAVQAGTGT GKSLAYLVPA
IKHAADGNGP VVVSTATIAL QRQLVDRDLP RLTAALTGTL PRTPSFALLK GRGNYLCLNK
LHTGGTGAEE AELPQEQLFN PATASALGRE VVRLNEWAQD TETGDRDELR PGVTDRAWGQ
VSVSARECLG PSRCPYATEC FSERARAEAG RADVVVTNHA LLAIDAIADA AVLPEHALLV
VDEAHDLVDR VTGVATGELT ATSMGTASRR SGRLIDAELT ERLDAAAATL SADLHERDAG
RIDILDEDLG RALTLLRDAA GAARSAIDTA PTDPKAAAAR SEAVAALDEV ADTAARMLDS
FGPAIPDRLD VVWLDREEIR GNTRVVLRVA PLSVAGLLRH RLFAETTTVL TSATLTLGGS
FDGMAGAWGL TSPDPEKSVR WRGLDVGSPF DHARSGILYI AKHLPPPGRD GSASEAQHRE
IAELIEAAGG RTLGLFSSMR AARAAADEMR QRLDTPVLCQ GEDATALLVE KFAADPQTSL
FGTLSLWQGV DVPGPSLSLV LIDRIPFPRP DDPLLTARQR AVAARGGNGF MAVAANHAAL
LLAQGAGRLL RRADDRGVVA VLDSRMATAR YGGYLRSSLP PFWTTTDGAR VRAALRRLRG
ADTESAPSPE
//
