ID A0A1X1TA96_9MYCO Unreviewed; 286 AA.
AC A0A1X1TA96;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Mycolic acid methyltransferase MmaA1 {ECO:0000313|EMBL:BBZ37482.1};
DE SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:ORV41415.1};
GN Name=cmaD {ECO:0000313|EMBL:BBZ37482.1};
GN ORFNames=AWC00_14455 {ECO:0000313|EMBL:ORV41415.1}, MCNS_05450
GN {ECO:0000313|EMBL:BBZ37482.1};
OS Mycobacterium conspicuum.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=44010 {ECO:0000313|EMBL:BBZ37482.1, ECO:0000313|Proteomes:UP000467385};
RN [1] {ECO:0000313|EMBL:ORV41415.1, ECO:0000313|Proteomes:UP000193407}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44136 {ECO:0000313|EMBL:ORV41415.1,
RC ECO:0000313|Proteomes:UP000193407};
RA Tarcisio F., Conor M., Antonella G., Elisabetta G., Giulia F.S., Sara T.,
RA Anna F., Clotilde B., Roberto B., Veronica D.S., Fabio R., Monica P.,
RA Olivier J., Enrico T., Nicola S.;
RT "The new phylogeny of the genus Mycobacterium.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BBZ37482.1, ECO:0000313|Proteomes:UP000467385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 14738 {ECO:0000313|EMBL:BBZ37482.1,
RC ECO:0000313|Proteomes:UP000467385};
RX PubMed=31287781;
RA Matsumoto Y., Kinjo T., Motooka D., Nabeya D., Jung N., Uechi K., Horii T.,
RA Iida T., Fujita J., Nakamura S.;
RT "Comprehensive subspecies identification of 175 nontuberculous mycobacteria
RT species based on 7547 genomic profiles.";
RL Emerg. Microbes Infect. 8:1043-1053(2019).
RN [3] {ECO:0000313|EMBL:BBZ37482.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 14738 {ECO:0000313|EMBL:BBZ37482.1};
RA Matsumoto Y., Motooka D., Nakamura S.;
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CFA/CMAS family.
CC {ECO:0000256|ARBA:ARBA00010815}.
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DR EMBL; AP022613; BBZ37482.1; -; Genomic_DNA.
DR EMBL; LQOR01000031; ORV41415.1; -; Genomic_DNA.
DR STRING; 44010.AWC00_14455; -.
DR OrthoDB; 9782855at2; -.
DR Proteomes; UP000193407; Unassembled WGS sequence.
DR Proteomes; UP000467385; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR003333; CMAS.
DR InterPro; IPR047672; CMAS_actinobact.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; NF040660; mycolic_MTase; 1.
DR PANTHER; PTHR43667; CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE; 1.
DR PANTHER; PTHR43667:SF1; CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE; 1.
DR Pfam; PF02353; CMAS; 1.
DR PIRSF; PIRSF003085; CMAS; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Methyltransferase {ECO:0000313|EMBL:BBZ37482.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:BBZ37482.1}.
FT ACT_SITE 268
FT /evidence="ECO:0000256|PIRSR:PIRSR003085-1"
SQ SEQUENCE 286 AA; 32829 MW; 242ED8D681821C6F CRC64;
MTELRPFYEE SQATYDISDD FFALFLDPNM VYTCAYFERD DMTLEQAQLA KIDLALDKLG
LEPGMTVLDV GCGWGGAVVR ALEKYDVNVI GVTLSRNHYE RTKARLAAVP TTRRAEARLQ
GWEEFDEPVD RIMTFEAFDA FKKDRWPAFF DRSYRMLPAD GRMLMHSIFS YPMSYYREHG
IPVTMTDVRF LRFLGTEIFP GGVMCSEPDI LDNARASGFA VDQSQYLQAH YVRTLETWAA
NLKASRERAI AIQSEEVYDK YMRYLTGCAG LFRKGISNVG QFTLVK
//
