ID A0A1X1TF21_9MYCO Unreviewed; 1167 AA.
AC A0A1X1TF21;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=ATPase {ECO:0000313|EMBL:BBZ08621.1};
DE SubName: Full=Nuclease {ECO:0000313|EMBL:ORV43153.1};
GN ORFNames=AWC01_06520 {ECO:0000313|EMBL:ORV43153.1}, MDOR_27900
GN {ECO:0000313|EMBL:BBZ08621.1};
OS Mycolicibacterium doricum.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=126673 {ECO:0000313|EMBL:ORV43153.1, ECO:0000313|Proteomes:UP000193564};
RN [1] {ECO:0000313|EMBL:ORV43153.1, ECO:0000313|Proteomes:UP000193564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44339 {ECO:0000313|EMBL:ORV43153.1,
RC ECO:0000313|Proteomes:UP000193564};
RA Tarcisio F., Conor M., Antonella G., Elisabetta G., Giulia F.S., Sara T.,
RA Anna F., Clotilde B., Roberto B., Veronica D.S., Fabio R., Monica P.,
RA Olivier J., Enrico T., Nicola S.;
RT "The new phylogeny of the genus Mycobacterium.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BBZ08621.1, ECO:0000313|Proteomes:UP000467201}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 12405 {ECO:0000313|EMBL:BBZ08621.1,
RC ECO:0000313|Proteomes:UP000467201};
RX PubMed=31287781;
RA Matsumoto Y., Kinjo T., Motooka D., Nabeya D., Jung N., Uechi K., Horii T.,
RA Iida T., Fujita J., Nakamura S.;
RT "Comprehensive subspecies identification of 175 nontuberculous mycobacteria
RT species based on 7547 genomic profiles.";
RL Emerg. Microbes Infect. 8:1043-1053(2019).
RN [3] {ECO:0000313|EMBL:BBZ08621.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 12405 {ECO:0000313|EMBL:BBZ08621.1};
RA Matsumoto Y., Motooka D., Nakamura S.;
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AP022605; BBZ08621.1; -; Genomic_DNA.
DR EMBL; LQOS01000019; ORV43153.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X1TF21; -.
DR STRING; 126673.AWC01_06520; -.
DR KEGG; mdr:MDOR_27900; -.
DR OrthoDB; 9757917at2; -.
DR Proteomes; UP000193564; Unassembled WGS sequence.
DR Proteomes; UP000467201; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd17934; DEXXQc_Upf1-like; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR019993; RecB_nuclease_TM0106_put.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR038720; YprB_RNase_H-like_dom.
DR NCBIfam; TIGR03491; TM0106 family RecB-like putative nuclease; 1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF6; RECBCD ENZYME SUBUNIT RECD; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF13604; AAA_30; 1.
DR Pfam; PF13482; RNase_H_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000193564}.
FT DOMAIN 321..509
FT /note="YprB ribonuclease H-like"
FT /evidence="ECO:0000259|Pfam:PF13482"
FT DOMAIN 943..1117
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
SQ SEQUENCE 1167 AA; 127042 MW; CB20E09FF6F2B706 CRC64;
MFVESVGAHD EATSSRVIYS ASDLAAAARC EYALLRSFDA RLGWGPKAAA DDGLLARTAD
LGEHHEKRHL EELRADGDNN VTVIGRPPYT VAGLTAAAEA TTRAVARRAP VIYQAAMFDG
RFAGFADFLV LAGDRYLLRD TKLARSVKVA ALLQLAAYAE TLTAVGVPVA DEVELVLGDG
ATARYALAEL LPVYRLRRAA LQRLLDDHLA GGAPVRWEDE DVRACFRCPE CSIQVRSRDD
PLLVAGMRVS QRARFLDAGV TTVAALAGHR GPVPELSART VAALSAQARL QIAPRVDGKP
PYEVTDPQPL MLLPEPDRGD LFFDFEGDPL WTDDGHEWGL EYLFGVLDTA DGFHPLWAHD
RPQERRALED FLEFVRKRRK RHPNMHIYHY AAYEKTALLR LAGRYGIGED AVDDLLRSGV
LVDLYPLVRK TFRVGTQNYS LKSLEPLYMG GQLRTGDVTT AAASITEYAR YCELRAEGRD
EDAAVVLKDI EDYNRYDCTS TRRLRDWLVC RAVDCEVPPR GPQPVRAELK PEPEPVDALD
RALCRYAGDE LQRRSPEQSA VAMVAAARGY HRREDKPFWW SHFDRLNNPV DEWADSTDVF
LVDADGAKVD TDWHTPPRAR KPQRRVRLTG AMAAGRLSRE MYALYEPPAP AGLGDDPDRR
AAGSATVVEY DDADAPTEVV IVERTPKDGG VFDQLPFALA PGPPIRTTAL RDSIEATAAE
VAERLPRLPA TAVTDILLRR PPRTRSGAPL PTGPDTPGTI TAALLDLDSS YLAVHGPPGT
GKTFTAAAVI ATLVNTHRWR IGVVAQSHAV VENLLRGVIA AGVASARVAK KRGHGDDACW
TVLDEAEFPA FCADNDGCVV GGTAWDFANG NRIPRGCLDL LVIEEAGQFC LANTIAVAPA
AANLLLLGDP QQLPQVSAGT HPEPVDSSAL GWLVDGAHTL PAERGYFLDV SYRMHPQVCA
AVSRLSYDGR LQSFDAVTAA RTLEGWSPGV HEVAVPHDGN ATESPEEADA IVARIRPLLN
ALWTDENGTR PLTEDDVMVV TPYNAQVVLL RQRLGAAGLA GVRVGTVDKF QGQQAPVVFV
SMVASSIDDV PRGISFLLNR NRLNVAISRA KYAAVIVRSE ALTEYLPSTP KGLVELGAFL
SLTTVAGQSP REWRPRGGSV VALSHWR
//
