ID A0A1X1V4P9_9MYCO Unreviewed; 330 AA.
AC A0A1X1V4P9;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:ORV64001.1};
GN ORFNames=AWC06_08215 {ECO:0000313|EMBL:ORV64001.1};
OS Mycobacterium fragae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1260918 {ECO:0000313|EMBL:ORV64001.1, ECO:0000313|Proteomes:UP000194000};
RN [1] {ECO:0000313|EMBL:ORV64001.1, ECO:0000313|Proteomes:UP000194000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45731 {ECO:0000313|EMBL:ORV64001.1,
RC ECO:0000313|Proteomes:UP000194000};
RA Tarcisio F., Conor M., Antonella G., Elisabetta G., Giulia F.S., Sara T.,
RA Anna F., Clotilde B., Roberto B., Veronica D.S., Fabio R., Monica P.,
RA Olivier J., Enrico T., Nicola S.;
RT "The new phylogeny of the genus Mycobacterium.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORV64001.1}.
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DR EMBL; LQOW01000005; ORV64001.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X1V4P9; -.
DR STRING; 1260918.AWC06_08215; -.
DR Proteomes; UP000194000; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ORV64001.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000194000};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 15..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 69..121
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT COILED 113..148
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 330 AA; 35937 MW; 7A999EA93FFE2E25 CRC64;
MDELRRRTRI PAGGLFRWVV LINGLIFTLG TLVLVMSPAT VSKPIKLAEI PVLGIGLAVM
LTANALLLRS KLAPLDRLAA SMRRVDPPRR SDRMHDRGDR DLHQLITSFN AMLDRLESER
TSASAAALAA QENERERIAR ELHDEIGQTL TVALLNLKRA IDRAPSGLLS DLENTQETVR
ASLDEVRGIA RRLRPDALED LGLPSALHAL CNEFAQASGI GVVKHIAPQA DRLKPDVELV
CYRIAQESLT NVARHSSAHK AWLDFHATPE KLTLRIADNG RGGAISEGAG ISGMRERALL
VNATLTISSP SNEGTEVRLV VPLGSIARSQ
//
