ID A0A1X1Y8C6_9MYCO Unreviewed; 281 AA.
AC A0A1X1Y8C6;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Dehydratase {ECO:0000313|EMBL:BBX98652.1};
GN Name=htdX {ECO:0000313|EMBL:BBX98652.1};
GN ORFNames=AWC15_20390 {ECO:0000313|EMBL:ORW07294.1}, MLAC_39460
GN {ECO:0000313|EMBL:BBX98652.1};
OS Mycobacterium lacus.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=169765 {ECO:0000313|EMBL:BBX98652.1, ECO:0000313|Proteomes:UP000466396};
RN [1] {ECO:0000313|EMBL:ORW07294.1, ECO:0000313|Proteomes:UP000193202}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44577 {ECO:0000313|EMBL:ORW07294.1,
RC ECO:0000313|Proteomes:UP000193202};
RA Tarcisio F., Conor M., Antonella G., Elisabetta G., Giulia F.S., Sara T.,
RA Anna F., Clotilde B., Roberto B., Veronica D.S., Fabio R., Monica P.,
RA Olivier J., Enrico T., Nicola S.;
RT "The new phylogeny of the genus Mycobacterium.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BBX98652.1, ECO:0000313|Proteomes:UP000466396}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15657 {ECO:0000313|EMBL:BBX98652.1,
RC ECO:0000313|Proteomes:UP000466396};
RX PubMed=31287781;
RA Matsumoto Y., Kinjo T., Motooka D., Nabeya D., Jung N., Uechi K., Horii T.,
RA Iida T., Fujita J., Nakamura S.;
RT "Comprehensive subspecies identification of 175 nontuberculous mycobacteria
RT species based on 7547 genomic profiles.";
RL Emerg. Microbes Infect. 8:1043-1053(2019).
RN [3] {ECO:0000313|EMBL:BBX98652.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 15657 {ECO:0000313|EMBL:BBX98652.1};
RA Matsumoto Y., Motooka D., Nakamura S.;
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254}.
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DR EMBL; AP022581; BBX98652.1; -; Genomic_DNA.
DR EMBL; LQPF01000077; ORW07294.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X1Y8C6; -.
DR STRING; 169765.AWC15_20390; -.
DR KEGG; mlj:MLAC_39460; -.
DR OrthoDB; 9774179at2; -.
DR Proteomes; UP000193202; Unassembled WGS sequence.
DR Proteomes; UP000466396; Chromosome.
DR GO; GO:0005835; C:fatty acid synthase complex; IEA:InterPro.
DR GO; GO:0004312; F:fatty acid synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR InterPro; IPR003965; Fatty_acid_synthase.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR002539; MaoC-like_dom.
DR PANTHER; PTHR43841; 3-HYDROXYACYL-THIOESTER DEHYDRATASE HTDX-RELATED; 1.
DR PANTHER; PTHR43841:SF1; 3-HYDROXYACYL-THIOESTER DEHYDRATASE X; 1.
DR Pfam; PF01575; MaoC_dehydratas; 1.
DR PRINTS; PR01483; FASYNTHASE.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000466396}.
FT DOMAIN 174..270
FT /note="MaoC-like"
FT /evidence="ECO:0000259|Pfam:PF01575"
FT REGION 149..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 281 AA; 30499 MW; A010B07F2242AA2F CRC64;
MNQPSGLKNL LRAAAGALPV VPRTDQLPNR TVTVEELPID HTNVAAYASV TGLRYGNTVP
LTYPFALTFP SVMSLVTGFD FPFAAMGAVH VENDITQYRP IAVTDTVGVR VHAENLREHR
KGLLVDLVTD VSVGNDPAWH QVTTFLHQQR TSLSDEPKPP PQKQPKLPPP GVVLRITPGK
IRRYAVVGGD HNPIHTNPIA ARLFGFPTVI AHGMFSAAAV LANIEARFPD AVRYSVRFAK
PVVLPATAGL YVEQCGDGWD LTLRNMSKGY PHLTGAVRAL L
//
