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Database: UniProt
Entry: A0A1X1Y922_9MYCO
LinkDB: A0A1X1Y922_9MYCO
Original site: A0A1X1Y922_9MYCO 
ID   A0A1X1Y922_9MYCO        Unreviewed;       394 AA.
AC   A0A1X1Y922;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   26-FEB-2020, entry version 8.
DE   SubName: Full=Polyketide synthase {ECO:0000313|EMBL:ORW07514.1};
GN   ORFNames=AWC15_19990 {ECO:0000313|EMBL:ORW07514.1};
OS   Mycobacterium lacus.
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=169765 {ECO:0000313|EMBL:ORW07514.1, ECO:0000313|Proteomes:UP000193202};
RN   [1] {ECO:0000313|EMBL:ORW07514.1, ECO:0000313|Proteomes:UP000193202}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44577 {ECO:0000313|EMBL:ORW07514.1,
RC   ECO:0000313|Proteomes:UP000193202};
RA   Tarcisio F., Conor M., Antonella G., Elisabetta G., Giulia F.S., Sara T.,
RA   Anna F., Clotilde B., Roberto B., Veronica D.S., Fabio R., Monica P.,
RA   Olivier J., Enrico T., Nicola S.;
RT   "The new phylogeny of the genus Mycobacterium.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORW07514.1}.
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DR   EMBL; LQPF01000075; ORW07514.1; -; Genomic_DNA.
DR   BioCyc; GCF_002102215:AWC15_RS09380-MONOMER; -.
DR   Proteomes; UP000193202; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synth_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synthase_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877; PTHR11877; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; SSF53901; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        340..360
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        372..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          33..236
FT                   /note="Chal_sti_synt_N"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          251..389
FT                   /note="Chal_sti_synt_C"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        175
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ   SEQUENCE   394 AA;  42598 MW;  4B18515B551B7E03 CRC64;
     MNTPFEGGAL CPAGDEPHYD LTQLPPAPPT TVAVIESIAT GAPRRVVDQA DAAARVASLF
     RDPGQRQRIP RIYRKTRITT RRMAVDPLDP EFDTFRRNRG TIRDRMNLYY RHAVPLAVEV
     GGRALAGLPY GVDEVGLLVF VTSTGFIAPG VDLAIVKELG LSRSISRVVI NFMGCAAAMN
     AIRLATSYVR AYPGMKAMVV GIELCSVNAV FADDVNDVVT HSLFGDGCAA MVIGAGRVHE
     KLEPGKVVIR SSFSRLLDDA EDGIVLGVNH NGITCELSEN LPEYIYAGVD PVVTEMLHDN
     GLQKSDIDLW AIHPGGPRII EESLRSLAIP PERAARSWDV LAGFGNMLSV SLIFVLEMMV
     RQAESTKAIS TGVAFAFAPG VTVEGMLFDI IRRP
//
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