ID A0A1X1YMH4_9MYCO Unreviewed; 422 AA.
AC A0A1X1YMH4;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Beta-ketoacyl-[acyl-carrier-protein] synthase II {ECO:0000313|EMBL:ORW12319.1};
GN ORFNames=AWC16_07820 {ECO:0000313|EMBL:ORW12319.1};
OS Mycolicibacter longobardus.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacter.
OX NCBI_TaxID=1108812 {ECO:0000313|EMBL:ORW12319.1, ECO:0000313|Proteomes:UP000193866};
RN [1] {ECO:0000313|EMBL:ORW12319.1, ECO:0000313|Proteomes:UP000193866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45394 {ECO:0000313|EMBL:ORW12319.1,
RC ECO:0000313|Proteomes:UP000193866};
RA Tarcisio F., Conor M., Antonella G., Elisabetta G., Giulia F.S., Sara T.,
RA Anna F., Clotilde B., Roberto B., Veronica D.S., Fabio R., Monica P.,
RA Olivier J., Enrico T., Nicola S.;
RT "The new phylogeny of the genus Mycobacterium.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; mycolic acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004796}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORW12319.1}.
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DR EMBL; LQPG01000011; ORW12319.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X1YMH4; -.
DR STRING; 1108812.AWC16_07820; -.
DR OrthoDB; 9808669at2; -.
DR UniPathway; UPA00915; -.
DR Proteomes; UP000193866; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProt.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022516};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 10..421
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 422 AA; 44405 MW; 911332472EEC0E12 CRC64;
MSTLATGNGL PNVVVTGITM TTALAANEEE TWKRLLDGQS GIRTLTDSFI EEYDLPVRIG
GHLVETPECF DEGLNRTELR RLSYLQKLST VLGRRVWAQV GEPEVDTRRL LVSIGTGMGS
SEELIWAYDG MRERGLKAVS PLVVQKYMPN GAAAAVGLDR QAKAGVITPI SACASGSEGI
AHAWQQIVLG EADIAICGGV ETRIEAVPIA GFAQMRIVLS NTNDNPEGAC RPFDRDRNGF
VFGEGAALMV IETEEHAKAR GANILARIMG ASITSDGYHI VAPDPDGQSA GRAMSRAIQL
AGLTPGDISH VNAHATGTSV GDVAEGHAIN LALGPHGGNA AVYAPKAALG HSVGAVGAVE
AILTVQALRD QVVPPTLNLE NLDPEIDLDV VAGEPRPGNY EYAINNSFGF GGHNVALVFG
RY
//
