ID   A0A1X1YYK5_9MYCO        Unreviewed;       320 AA.
AC   A0A1X1YYK5;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Cation diffusion facilitator family transporter {ECO:0000313|EMBL:ORW16189.1};
GN   ORFNames=AWC17_15625 {ECO:0000313|EMBL:ORW16189.1};
OS   Mycobacterium nebraskense.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=244292 {ECO:0000313|EMBL:ORW16189.1, ECO:0000313|Proteomes:UP000193781};
RN   [1] {ECO:0000313|EMBL:ORW16189.1, ECO:0000313|Proteomes:UP000193781}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44803 {ECO:0000313|EMBL:ORW16189.1,
RC   ECO:0000313|Proteomes:UP000193781};
RA   Tarcisio F., Conor M., Antonella G., Elisabetta G., Giulia F.S., Sara T.,
RA   Anna F., Clotilde B., Roberto B., Veronica D.S., Fabio R., Monica P.,
RA   Olivier J., Enrico T., Nicola S.;
RT   "The new phylogeny of the genus Mycobacterium.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORW16189.1}.
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DR   EMBL; LQPH01000164; ORW16189.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X1YYK5; -.
DR   OrthoDB; 9809646at2; -.
DR   Proteomes; UP000193781; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR   InterPro; IPR002524; Cation_efflux.
DR   InterPro; IPR036837; Cation_efflux_CTD_sf.
DR   InterPro; IPR027469; Cation_efflux_TMD_sf.
DR   NCBIfam; TIGR01297; CDF; 1.
DR   PANTHER; PTHR11562; CATION EFFLUX PROTEIN/ ZINC TRANSPORTER; 1.
DR   PANTHER; PTHR11562:SF17; LD05335P; 1.
DR   Pfam; PF01545; Cation_efflux; 1.
DR   SUPFAM; SSF160240; Cation efflux protein cytoplasmic domain-like; 1.
DR   SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        20..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        51..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        88..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        119..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        163..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        187..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   320 AA;  33334 MW;  EEC05F25056541C6 CRC64;
     MSGGHSHTHG NTSADSDRRW LAGAFAVIAT FMLGEVAVGV VAGSLALLSD AAHMLTDAAS
     IALALWAIRL AARPAAGRMT YGWRRVEILS AQANGVTLLV LAGWLGYEAI KRLVHPPQVT
     GTLVLVTALV GVVVNVAATW MISRANRSSL NVEGAFQHIL NDLFAFIATA VAGVVIVFTG
     FGRADAIATL VVVALMIRAG VGLVRAASLV FLEAAPSGIE PDVIGQAMAD HDSVVEVHDL
     HVWEITSGTP ALSAHVIVAA DHDCHATRND LAQLLAHEHG ISHTTLQLDH EISEIGDRGM
     GAACAPCDDP HGPTHRAVGT
//