ID A0A1X2C6U4_9MYCO Unreviewed; 538 AA.
AC A0A1X2C6U4;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=FAD-binding protein {ECO:0000313|EMBL:BBX63483.1};
GN ORFNames=AWC23_13200 {ECO:0000313|EMBL:ORW71715.1}, MSAS_26570
GN {ECO:0000313|EMBL:BBX63483.1};
OS Mycobacterium saskatchewanense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium simiae complex.
OX NCBI_TaxID=220927 {ECO:0000313|EMBL:BBX63483.1, ECO:0000313|Proteomes:UP000467517};
RN [1] {ECO:0000313|EMBL:ORW71715.1, ECO:0000313|Proteomes:UP000193387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44616 {ECO:0000313|EMBL:ORW71715.1,
RC ECO:0000313|Proteomes:UP000193387};
RA Tarcisio F., Conor M., Antonella G., Elisabetta G., Giulia F.S., Sara T.,
RA Anna F., Clotilde B., Roberto B., Veronica D.S., Fabio R., Monica P.,
RA Olivier J., Enrico T., Nicola S.;
RT "The new phylogeny of the genus Mycobacterium.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BBX63483.1, ECO:0000313|Proteomes:UP000467517}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 13016 {ECO:0000313|EMBL:BBX63483.1,
RC ECO:0000313|Proteomes:UP000467517};
RX PubMed=31287781;
RA Matsumoto Y., Kinjo T., Motooka D., Nabeya D., Jung N., Uechi K., Horii T.,
RA Iida T., Fujita J., Nakamura S.;
RT "Comprehensive subspecies identification of 175 nontuberculous mycobacteria
RT species based on 7547 genomic profiles.";
RL Emerg. Microbes Infect. 8:1043-1053(2019).
RN [3] {ECO:0000313|EMBL:BBX63483.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 13016 {ECO:0000313|EMBL:BBX63483.1};
RA Matsumoto Y., Motooka D., Nakamura S.;
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; AP022573; BBX63483.1; -; Genomic_DNA.
DR EMBL; LQPR01000028; ORW71715.1; -; Genomic_DNA.
DR STRING; 220927.AWC23_13200; -.
DR KEGG; msak:MSAS_26570; -.
DR OrthoDB; 9813348at2; -.
DR Proteomes; UP000193387; Unassembled WGS sequence.
DR Proteomes; UP000467517; Chromosome.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 8..515
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 538 AA; 56148 MW; E333887C5BF8B23C CRC64;
MSWDEEVDVI VLGSGGAGLT AALTAAGAGA SVAVFEKAPT VGGTTAVSGG VVWIPAHNRS
PDGELTVADA LRYLRAQSLG SMDAAAVETF VRTGPAMLDF VEEHSGVRFE IATGFPDYRP
ELPGGRPAGG RSLSPAPFDL ARLGQWATRI TAFPADWSNV GFDAETRARL HAAIDECTGR
LGVAGTALIA GLLEGLLTAG VVPHTNARAE RLLTDEGEVT GARIALTDRT VDVRARQGVI
LGTGGFEWNP VLVQAFLRGP MHGAVSPPNN TGDGLRMAME HGADLANMGE AWWVPIVQIP
GDTIDGKPRS RSVRLERTRP RSIIVNAAGR RFVNEACDYN SMAGAFHYLD PRGGYVNDRG
WMVFDSIHLQ RYGFLGVAPG DPVPDWFCES ADLAELAAKA GIEADGLART VEQWNRQVAD
GADAEFGRGS SAYDGYWGDD TATTLAGKTL GPIDTAPFYA VPVRIGAMGT KGGPRTDHDG
RVLHVSGEPI AGLFAAGNAM GGVTGRAYGG AGGTLGPAMV FGYRAGHAAA TGKSVDLK
//
