ID A0A1X2G6P9_9FUNG Unreviewed; 552 AA.
AC A0A1X2G6P9;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=P-loop containing nucleoside triphosphate hydrolase protein {ECO:0000313|EMBL:ORX46507.1};
GN ORFNames=DM01DRAFT_1386180 {ECO:0000313|EMBL:ORX46507.1};
OS Hesseltinella vesiculosa.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Cunninghamellaceae; Hesseltinella.
OX NCBI_TaxID=101127 {ECO:0000313|EMBL:ORX46507.1, ECO:0000313|Proteomes:UP000242146};
RN [1] {ECO:0000313|EMBL:ORX46507.1, ECO:0000313|Proteomes:UP000242146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 3301 {ECO:0000313|EMBL:ORX46507.1,
RC ECO:0000313|Proteomes:UP000242146};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORX46507.1}.
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DR EMBL; MCGT01000037; ORX46507.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X2G6P9; -.
DR OrthoDB; 1384128at2759; -.
DR Proteomes; UP000242146; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR037359; NST/OST.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10605:SF56; BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE; 1.
DR PANTHER; PTHR10605; HEPARAN SULFATE SULFOTRANSFERASE; 1.
DR Pfam; PF13469; Sulfotransfer_3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ORX46507.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242146};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 59..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 442..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..467
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..504
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 262
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
SQ SEQUENCE 552 AA; 63864 MW; 57B7692AA8F263A7 CRC64;
MVTMFKQNQL HHFETAVSPV LRKKQQPGMQ AKRLHLDNEA LSTSSPHSSR HYASSRSKYR
LCQALSLVTF MLVLLLIYIV HTTPLSIFQA DGGKTSLASL VSKRTLQRWH GYLSSRFFDA
TASPPKLYYP PHCPSPSDRQ ESITCAKPVP SFIFAGSEMS GSRYIFEQLQ HHPQVAWTMD
ASASPHVTSL DDDLFDDQKN GKDAFETYLS QFPFLTDREL ANIEKQQVIV GEHAPHYLYK
SFVTARRIKE MLPHVKLVFI LRDPIDRAYT QFIREMSILR RKQQQQHHEQ PNADSPSLSF
EDLIDLEMTI LEHCRASGAH NDWESFLRCH RSSDIRASWN LTITDQQDHH LEIYDGLVKG
MYYNSLVPFL QHFGPSQLYV TRTEDFINNP SMSFQRLAKF LGIQEDYFSE LNFYGRLALA
QQQETPLSEE ADDLIHMILQ QQHYHHQKQQ HQQQQTHRNR HSSNTRHRPQ QRVPAMALEE
EATMPAASST SNAAPSSSPL LPSINKDDDQ DALDLSIRYR LEKIFRPLNE QLLSLFEDHK
DFLGWDYDVD RG
//
