ID A0A1X2G7I1_9FUNG Unreviewed; 930 AA.
AC A0A1X2G7I1;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=PH-domain-containing protein {ECO:0000313|EMBL:ORX46273.1};
GN ORFNames=DM01DRAFT_1410644 {ECO:0000313|EMBL:ORX46273.1};
OS Hesseltinella vesiculosa.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Cunninghamellaceae; Hesseltinella.
OX NCBI_TaxID=101127 {ECO:0000313|EMBL:ORX46273.1, ECO:0000313|Proteomes:UP000242146};
RN [1] {ECO:0000313|EMBL:ORX46273.1, ECO:0000313|Proteomes:UP000242146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 3301 {ECO:0000313|EMBL:ORX46273.1,
RC ECO:0000313|Proteomes:UP000242146};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORX46273.1}.
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DR EMBL; MCGT01000038; ORX46273.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X2G7I1; -.
DR STRING; 101127.A0A1X2G7I1; -.
DR OrthoDB; 1367385at2759; -.
DR Proteomes; UP000242146; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd09535; SAM_BOI-like_fungal; 1.
DR CDD; cd00174; SH3; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR045188; Boi1/Boi2-like.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR22902:SF27; INOSITOL PHOSPHATASE INTERACTING PROTEIN, ISOFORM A; 1.
DR PANTHER; PTHR22902; SESQUIPEDALIAN; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF07647; SAM_2; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00233; PH; 1.
DR SMART; SM00454; SAM; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000242146};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 2..65
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 175..238
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 478..574
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 796..905
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 94..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 237..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 298..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 721..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 756..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 237..251
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..273
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 621..635
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..689
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 930 AA; 102968 MW; D45777CBE09A1171 CRC64;
MAGLETVYAT HNFEADNPDE ITFHLGEPIL VLEKDEGYQD GWWQGRNVRG EIGLFPKNYT
SLRKPSNSSS LSTLESKIDS LESTVSQMHI QKKGGGLLLP TPSASNSSQQ SAFNTPQPLY
FPSSASSTSS RHTAAGGPNA PSASYQKKLS TKYVHHSVAT SLQNPELSPN LPEDWSVDQV
AIWLGLMGFS DMAPTFQDQE ITGDILLELN VDTLKELGVS TFGKRFKISN AIKVLGEENS
QRKDDRQAGS PADDRSNSLS SQHHGSPTLS SVAPLRLGQP FLDEEDAVSD YAGVLRSTQH
MPPASTPRLQ PSLSPTAPSI ASTSSLVRSP SLQQQPVSTR DTGRQPSTTS SLAHTPILED
EPLTTRGVMS MDVPRHVSPR AQTPLNRALS TNQAYGHWSN NNVSRMQSNG GATVIQPPTQ
QPVSYRASTQ PTTTIHPIDQ KPRGFVRNSL LPTSIRASMD GIAQRLTQQK QQQAQQDLPD
LEGWLHKQSD RYRTWNKRWF VLKGTNLFYF KSPKETRMKG IINLRGYRIE QDPSIHTGKY
CFKAQHERER TFYFYTESER NLREWLKALT KATITRDYSA PVMSSSTVPT VSLATAQRMK
PRPPSRVYTK DREPAVMDVN LPSTDASQEP QPIMRMSMSD DSRHMYAPAT PTASLSTEMP
ASPPQPRPLA TSPPLLPVHQ PPFPSHTQQP QPSPHQSTVA DTSIYSSLFY NDEEEDLIDP
HQIAPRGADQ TTPSRAIDKQ PVHRMDNSPV IRHFPASPMA PDAADPARSV LDDPPAEDAS
PPTLLTVPSA STSSEHWSAQ DFVDWMNQHM DSSRFHQVTE LRTGEPLVDL LESISGKEIR
RPASAQRQGS GTLTSMQMLD NIVAAFKFMG REGVVVDGRY TIKDVFNGND EKILEMLRTI
KDWAELLHPS TEKMASGGTF GEEEDMLKQL
//
