ID A0A1X2GLP9_9FUNG Unreviewed; 2049 AA.
AC A0A1X2GLP9;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 08-NOV-2023, entry version 24.
DE RecName: Full=Rap-GAP domain-containing protein {ECO:0000259|PROSITE:PS50085};
GN ORFNames=DM01DRAFT_1335187 {ECO:0000313|EMBL:ORX55802.1};
OS Hesseltinella vesiculosa.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Cunninghamellaceae; Hesseltinella.
OX NCBI_TaxID=101127 {ECO:0000313|EMBL:ORX55802.1, ECO:0000313|Proteomes:UP000242146};
RN [1] {ECO:0000313|EMBL:ORX55802.1, ECO:0000313|Proteomes:UP000242146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 3301 {ECO:0000313|EMBL:ORX55802.1,
RC ECO:0000313|Proteomes:UP000242146};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORX55802.1}.
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DR EMBL; MCGT01000011; ORX55802.1; -; Genomic_DNA.
DR STRING; 101127.A0A1X2GLP9; -.
DR OrthoDB; 21929at2759; -.
DR Proteomes; UP000242146; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR InterPro; IPR046859; RGPA/RALGAPB_N.
DR InterPro; IPR027107; Tuberin/Ral-act_asu.
DR PANTHER; PTHR10063:SF11; RHO GTPASE-ACTIVATING PROTEIN CG5521-RELATED; 1.
DR PANTHER; PTHR10063; TUBERIN; 1.
DR Pfam; PF20412; RALGAPB_N; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000242146}.
FT DOMAIN 1819..2028
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 475..538
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 736..761
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 857..925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 953..1004
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1658..1694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 857..886
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 901..923
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..1001
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1658..1675
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2049 AA; 228944 MW; 823AC1BF479A5082 CRC64;
MPTTTASTDH LPDASTQDFP LPSSSTAIKE DHPEKLRKKL KVFLDEKQKV KSRLQSLWSY
LDAIDSFDQC RFTQEYYEQV FHVVHEACIQ QIDKMKQRHE RPQTWHAKEM VSLQKMLLLL
RKIFLFVPEM MRNGWQRQNI ATLLAHILDH GNHIRLRALG FHLLLLWLND QVVEYPECMQ
LFANALSLDL FIMDDISASS EDPLQQETDN NPSTDDSSNL LTNALPFVKK LSDRHAEKLS
GYGLVRNDRV KQANIHLQQS FIHGDDHDPL FPSPVPPTFH DSLVLFNIFI TNLVRLASVA
AGSPPPPDNY DYPEQCEPDE GIATGTGIDA ATASAKFLFK IFRTYYMTKF VPHIASELQM
EGATKTDSNQ PVGFPRCPPS ILRTVLRFLI GYCLDNNHSA QVYWPNLPAQ ATSSPATPIL
KSIVLSSHET REMLHDMIRQ CMLLPTSNAN YWDITRGALH IIGVWSLGNE DERPSFLRPP
GATPGMIRST SSTSLTKYHE KKPKPTPPLL PVASSHSLED LPLSPPPQQK RHTPQPHQQS
EANVFLRRYF TMIQLIFDQP SATVLDPEFD WDGLVNLYKD AINVYRSITV TRGGIEMEWE
SWECLLRCVM CIQKWIMAAP TQTSRIAMPA LADDFVDYLC ETVFYAFARA RIAHSELWHE
LQQLLLAGLD RWQVLDQWTK IMYKITKVLS HKLYKVDYDV IYRTPSQFYL DKSGSVPNRL
SGSFYDANAA NATGVRRSRT RHLSIQDEQN NPSRAASSKI FGNRPISIGT SNVASVSEGE
LLDLPACQPH QHILDLASGF PLPPGVVEVP LPPAPSTMPN MLPLEEDKPT APSNSISTGR
KFGIKNIIPA TSFSSSHTSS LLVPQNGPSA SSVSTSGHLT HSSPTHHHPP LTRHGNDSVE
KVQHTPLSPT RATSVSSAPG SRRGRRTVSI HQFDHLFQES GSKLLNFVHA SASQSGASTP
SHPSTTDAGA SDLLGTHHDT PQPSTSKLNL GSNSSVAYKD DEGANTQKRK GLIIDWDRRS
NGSTNLTLSS KSNRTSASTI LAPTEMITMK ITPADVNDKL PADLGIFRSS EFLNLHNLPW
DGPGTQIIWM NLLCSLGNIN KIESPQRHDL AMRCVVDIWD TLIWVRDNQP YRGLPTPALY
DITSWLLQGT ELPSGFNAGR SKAYGCLCRL VCRKTRAPQS KEFYAHFYRT ILKGLTSDDS
QIIQAIIQNC ERLFTFSLPG AHILIPPFIH TIEKQLVVGG KAAKVPLSVR KSCITILGSL
TSVSNQFSDV QLGVKTGDGQ CTDTKQLKFS DVKIWLKNLF IQLVDVDPAT TLCEEETEVH
CMLLGATCSL IMDELLATKT PQRSLIQECI TVLVSHLYWC NISVINAVVD CLVLISQIYN
RTLDPEGDII QEVLTRIIDA LNVQLKFYKS NVRSGRGIII AKLFTCILEW LMIIEPEILT
DTELCQLVFD VIDEAMHFSA GGRAEKMLPH PPLIRKSSRA KKKEVPFKFL LTEKRPQVMQ
DPTPTDSSEV NQADQSCVND AAEAVLLHLL HHFNNFPPPY GPATACSTIV GPGLSSSTDD
KNDIEYRHFQ YFSFNDTTII AFVELPPTDT KPAETRIVIR DLTGRYAWDA HLEPPFCDSP
LTFSPLDDGA KFEAAEDHLL EREQGFTLRP GLLVKKRDQS SHSSLTSSPD TLSSLLQDIG
EDHPDCMSSS NVSMTSPSTL SSLQVGMLGR LSEQLNDFLT SECDNHQQRE SDPRVWYAKL
NAVQRRSSQT PAPTSSLLST NFSAQKDFCP ALPRDPEKTN VPFQQSRLLI SHLGLLSYSQ
LKDGSFQMLN KTSALFRDLR GLDRKPGHET MKIGLMYVGA DQEDEQSILH NNSGSAAYDA
FVKSLGWEID IAKHTGYLGG LERNLTNGNK ATYFCSSTVE IIFHDVTKMP TDVNDPKQLK
KKRHIGNDHV HIVWNEHNRD YHVGTIGGDF GNAQIVVTPL PDGLYSIHLH RDPKIPMFGP
LFNQMTVSHA TLGPMVRATA IAACRACVHT NTPSIISQRA RDVKTITQRH KVATWSYEQF
VERIFLPED
//
