ID   A0A1X2GUP9_9FUNG        Unreviewed;       526 AA.
AC   A0A1X2GUP9;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Cyclophilin-like protein {ECO:0000313|EMBL:ORX61752.1};
GN   ORFNames=DM01DRAFT_1299830 {ECO:0000313|EMBL:ORX61752.1};
OS   Hesseltinella vesiculosa.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Cunninghamellaceae; Hesseltinella.
OX   NCBI_TaxID=101127 {ECO:0000313|EMBL:ORX61752.1, ECO:0000313|Proteomes:UP000242146};
RN   [1] {ECO:0000313|EMBL:ORX61752.1, ECO:0000313|Proteomes:UP000242146}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 3301 {ECO:0000313|EMBL:ORX61752.1,
RC   ECO:0000313|Proteomes:UP000242146};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the cyclophilin-type PPIase family. CWC27
CC       subfamily. {ECO:0000256|ARBA:ARBA00038509}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORX61752.1}.
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DR   EMBL; MCGT01000003; ORX61752.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X2GUP9; -.
DR   STRING; 101127.A0A1X2GUP9; -.
DR   OrthoDB; 1328057at2759; -.
DR   Proteomes; UP000242146; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   CDD; cd01925; cyclophilin_CeCYP16-like; 1.
DR   Gene3D; 2.40.100.10; Cyclophilin-like; 1.
DR   InterPro; IPR029000; Cyclophilin-like_dom_sf.
DR   InterPro; IPR020892; Cyclophilin-type_PPIase_CS.
DR   InterPro; IPR002130; Cyclophilin-type_PPIase_dom.
DR   InterPro; IPR044666; Cyclophilin_A-like.
DR   PANTHER; PTHR45625; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED; 1.
DR   PANTHER; PTHR45625:SF6; SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG; 1.
DR   Pfam; PF00160; Pro_isomerase; 1.
DR   PRINTS; PR00153; CSAPPISMRASE.
DR   SUPFAM; SSF50891; Cyclophilin-like; 1.
DR   PROSITE; PS00170; CSA_PPIASE_1; 1.
DR   PROSITE; PS50072; CSA_PPIASE_2; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242146}.
FT   DOMAIN          22..167
FT                   /note="PPIase cyclophilin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50072"
FT   REGION          214..291
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          314..357
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          442..526
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        214..237
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        252..289
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        314..337
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        463..526
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   526 AA;  60375 MW;  40D60A4685851D2A CRC64;
     MSNIYALEPY TNGKVILKTT KGDVEIELWG KEAPKATRNF IQLCLEGYYD DTIFHRVVPG
     FIVQGGDPTG TGFGGESIYE DSEFPDEFHS RLRFNRRGLV GMANTGQNDN GSQFFFTLDR
     SDDLTKKHTL FGRVAGDTLF NVMKMAELEI DKDNRPLYPP KIKSTEVVIN PFDDIVPRVS
     KKELLAQQER ERLLAEAAKP KKVKKEKKRL NLLSFGEEAE EMSPETTKKK MKSAHDDMEG
     VPAPAPLPPS IEKELERLRQ EKAQPKPEAE PSEMTKPSKP KKEKASIDQP TLSAKEQIEI
     LKRDIKQISK VEEKVVDNSS KKKVSLVQQE REKYAKSGKV SIGGMKARKR KGMSDDDTMA
     RLMAFQDKLT STEEAAPLRK KENGPCALHG IPGCESCESN VGDLFAEDDS PDNWMAHKLV
     FEKDLKGKDL MQRKENVNDY VVFDPLDKNN QEQDPLDASY SKRQQNDSRR SSSHRSDRDR
     HDDYQKRRRD DDRRSRYDDR DGDYRRRRDD GAYSRKRSER RDDSRR
//