ID A0A1X2H1A8_SYNRA Unreviewed; 440 AA.
AC A0A1X2H1A8;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Endopeptidase S2P {ECO:0000256|ARBA:ARBA00032658};
GN ORFNames=BCR43DRAFT_498714 {ECO:0000313|EMBL:ORY91217.1};
OS Syncephalastrum racemosum (Filamentous fungus).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Syncephalastraceae; Syncephalastrum.
OX NCBI_TaxID=13706 {ECO:0000313|EMBL:ORY91217.1, ECO:0000313|Proteomes:UP000242180};
RN [1] {ECO:0000313|EMBL:ORY91217.1, ECO:0000313|Proteomes:UP000242180}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2496 {ECO:0000313|EMBL:ORY91217.1,
RC ECO:0000313|Proteomes:UP000242180};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY91217.1}.
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DR EMBL; MCGN01000011; ORY91217.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X2H1A8; -.
DR STRING; 13706.A0A1X2H1A8; -.
DR InParanoid; A0A1X2H1A8; -.
DR OMA; FYSWGRW; -.
DR OrthoDB; 51250at2759; -.
DR Proteomes; UP000242180; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR InterPro; IPR001193; MBTPS2.
DR InterPro; IPR008915; Peptidase_M50.
DR PANTHER; PTHR13325:SF3; MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-2 PROTEASE; 1.
DR PANTHER; PTHR13325; PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASE; 1.
DR Pfam; PF02163; Peptidase_M50; 1.
DR PRINTS; PR01000; SREBPS2PTASE.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242180};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..440
FT /note="Endopeptidase S2P"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012145921"
FT TRANSMEM 363..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..439
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 66..231
FT /note="Peptidase M50"
FT /evidence="ECO:0000259|Pfam:PF02163"
SQ SEQUENCE 440 AA; 48284 MW; DF2CE3BBAD639098 CRC64;
MIFSLGVIAY AACHVLSGLL RLPTAASAST VAHIKRSLDD TNSRSNDQVF LPMIPGVTLP
MSHITYYLFA LLICGIIHEA GHAIASYSER VPIKSAGIFV YYIYPGAFVN IPDQPLQLLA
PKSQLRIVCA GVWHNAVLYL VTLLLLSGGL KSCLEIAGWQ SLESEGGVSV VTVRPDSPLA
VHLQLSSVIY QLDDLPLQRN ILDWNAYLLE DGGKHVPDAG FCAPITSVTE DLACCEIDNE
FPFGKAANAT VSCFTNFDIQ TSPFKSCFTT TDILLAPERQ RCNRDTDCLQ TGQRCVMPYT
PSEAGQIVRL HVRMPPWYPA SEKDKMFVFE GELVDIWESV KVGLLRPRFR ILPVSLPHMS
ELLLQYISSF TLALAILNIL PVFQLDGQYA LEQLVHCWQP SVTTQSTRSQ RAAQNIIKGT
TVLVGFVLVG SIFLGVLGAA
//
