ID   A0A1X2H406_SYNRA        Unreviewed;       414 AA.
AC   A0A1X2H406;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:ORY93123.1};
GN   ORFNames=BCR43DRAFT_526732 {ECO:0000313|EMBL:ORY93123.1};
OS   Syncephalastrum racemosum (Filamentous fungus).
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Syncephalastraceae; Syncephalastrum.
OX   NCBI_TaxID=13706 {ECO:0000313|EMBL:ORY93123.1, ECO:0000313|Proteomes:UP000242180};
RN   [1] {ECO:0000313|EMBL:ORY93123.1, ECO:0000313|Proteomes:UP000242180}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 2496 {ECO:0000313|EMBL:ORY93123.1,
RC   ECO:0000313|Proteomes:UP000242180};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00038048}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY93123.1}.
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DR   EMBL; MCGN01000009; ORY93123.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X2H406; -.
DR   InParanoid; A0A1X2H406; -.
DR   OMA; CEYRAIA; -.
DR   OrthoDB; 5479972at2759; -.
DR   Proteomes; UP000242180; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR12286:SF5; SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR12286; UNCHARACTERIZED; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242180};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        276..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          8..139
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
SQ   SEQUENCE   414 AA;  46254 MW;  8BCBCDEAAE65A206 CRC64;
     MSRTYDLVIF GATGFTGSLV CEYLVQSSNK DVRWAIAGRN SKKLQDVKAK LVELDSECES
     RVDILIGDSG DRESLDRIVR QTRVVLSTVG PFTKYGGPLV EACVENKTHY IDSTGEYNFV
     KSLIDKHHEK ARQEGTFIVP CCGFDSIPSD LGTFMVCDYI RKKHNIGIEN VKCSVVSFEG
     GLSGGTYQSF VEVMGDDNIS LMQSLDPYLL SPMRGKDSIP SIMMRRDKDF DKRWQTFWAM
     APTNERIVRR TWALLAERGE GYGPAFRYHE TLSMKFFSAF AFTTVMVLLG PLIIPLLRMR
     LTRNRVAKLL PTSGEGPTRE EIENSTWEVQ LVATSEKGSS NQSVRVRGTV KGFKHGGYGD
     TARMLIESAL CLVKDHDMLP AKEGGVLTTA SAFGNVLLER LRADGKMIFE TEEL
//