ID A0A1X2H726_SYNRA Unreviewed; 598 AA.
AC A0A1X2H726;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Acyltransferase ChoActase/COT/CPT {ECO:0000313|EMBL:ORY94251.1};
GN ORFNames=BCR43DRAFT_496121 {ECO:0000313|EMBL:ORY94251.1};
OS Syncephalastrum racemosum (Filamentous fungus).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Syncephalastraceae; Syncephalastrum.
OX NCBI_TaxID=13706 {ECO:0000313|EMBL:ORY94251.1, ECO:0000313|Proteomes:UP000242180};
RN [1] {ECO:0000313|EMBL:ORY94251.1, ECO:0000313|Proteomes:UP000242180}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2496 {ECO:0000313|EMBL:ORY94251.1,
RC ECO:0000313|Proteomes:UP000242180};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY94251.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MCGN01000008; ORY94251.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X2H726; -.
DR STRING; 13706.A0A1X2H726; -.
DR InParanoid; A0A1X2H726; -.
DR OMA; QCSEFLM; -.
DR OrthoDB; 1429709at2759; -.
DR Proteomes; UP000242180; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589:SF115; CARNITINE O-ACETYLTRANSFERASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00439; ACYLTRANSF_C_1; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:ORY94251.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000242180};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ORY94251.1}.
FT DOMAIN 27..558
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT ACT_SITE 319
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 598 AA; 66954 MW; A57CC5B4DDF8AA60 CRC64;
MAPQPKTPVD PNAPGPMLRY QSNLPRLPVP KVQETIAKYL NTVKAVVSEE QYKRTEQAAK
EFISSGAADK LQARLVARAE DPKVLNWMDD WWLDAAYLGY RDPVVVFVSY FYLYKDDKLR
KSPAQRAAAM TTAALAFREQ VVGNTLEPEY AKGEPLCMDR YKYMFNNCRI PAKPSDVNAA
YNPAQNTHII VIRKNKFFVV DTVLNGRQLS TGELEYQFHR VIEAAGYGKG VPIGAFTADN
RDNWADNRKA LLAAHPENKK ILEKIESSAF VVCLDDSSPV SRDEGSRACW HGDGRNRFFD
KPCQFIVYEN GKAGFMGEHA MMDGTATCRL NEFVCDFISK SKVEMIANAN NKLPEPAELS
FRINNDIGKA LHAAERRFDE LVGSYDLTVC AFQQFGKNQM VIQLAYYKMF GVCRPTYESA
QTRKFQLGRT ETSRTVSADS IAFVKAMENP HLPVADKIAA FRKAIKTQGA YMGQCVNAHG
VDRHLFGLKK CLAANEPVPA LFSDPSYAYS SHWFLSTSQL SSEYFDGYGW GPVVADGFGI
AYMIKNNSFH FNITTLKSLD IDGVLFTNAA EKLKQCLEDA ASELRDVLIT EVQTPAKL
//
