ID A0A1X2H8G7_SYNRA Unreviewed; 956 AA.
AC A0A1X2H8G7;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
GN ORFNames=BCR43DRAFT_441888 {ECO:0000313|EMBL:ORY94808.1};
OS Syncephalastrum racemosum (Filamentous fungus).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Syncephalastraceae; Syncephalastrum.
OX NCBI_TaxID=13706 {ECO:0000313|EMBL:ORY94808.1, ECO:0000313|Proteomes:UP000242180};
RN [1] {ECO:0000313|EMBL:ORY94808.1, ECO:0000313|Proteomes:UP000242180}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 2496 {ECO:0000313|EMBL:ORY94808.1,
RC ECO:0000313|Proteomes:UP000242180};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORY94808.1}.
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DR EMBL; MCGN01000007; ORY94808.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X2H8G7; -.
DR STRING; 13706.A0A1X2H8G7; -.
DR InParanoid; A0A1X2H8G7; -.
DR OMA; QTEFPVP; -.
DR OrthoDB; 1032627at2759; -.
DR Proteomes; UP000242180; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.102.20.10; Beta-galactosidase, domain 2; 1.
DR Gene3D; 2.60.390.10; Beta-galactosidase, domain 3; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR018954; Betagal_dom2.
DR InterPro; IPR037110; Betagal_dom2_sf.
DR InterPro; IPR025972; BetaGal_dom3.
DR InterPro; IPR036833; BetaGal_dom3_sf.
DR InterPro; IPR025300; BetaGal_jelly_roll_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF13364; BetaGal_ABD2; 2.
DR Pfam; PF10435; BetaGal_dom2; 1.
DR Pfam; PF13363; BetaGal_dom3; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SMART; SM01029; BetaGal_dom2; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF117100; Beta-galactosidase LacA, domain 3; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ORY94808.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000242180};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..956
FT /note="beta-galactosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012959346"
FT DOMAIN 390..539
FT /note="Beta-galactosidase"
FT /evidence="ECO:0000259|SMART:SM01029"
SQ SEQUENCE 956 AA; 106644 MW; 248CA8E54626CAD4 CRC64;
MALAKCVFTS ITAAIMATAV LAIPAPLQFD KRDSFDKPVT WDNHTLMING ERLFLYSGEF
HYYRLPSPGL WVDIMEKFKA LDFNGVSFYF YWGYHSPKKG IYDFSGVRDV QKAIDAATQA
DLEIITRPGP YINAEVDGGG FPGWTKTQRA VARKNSTENN ENWSEWLSAI DAKIVPNQIT
HGGRVILNQI DNEYAANTDE YYMEAIKEQF LKDGMDVPTI FNDPNTGAHF VHGIGAPDIY
GWDSYPAGFD CSNPDVWPNN ANFGWYDYHM ANNPDQPVAL YEFQGGAFDP WGGPGYDACR
KMVSERYAKV YYKNNYANGA RIQNLYMGYG TSWGGIAIPS VYTSYDYGAP ISEPGLMTPK
AHEVRLQGME ALSCIPSSLS CLPTDSMPQW IMMTSILMAG SIKRQARRST FKAAGKTINI
PRSSKLVLNG RDAKMLVADY AFNSQELAYT TSEIFTHQSM GSFDVLLVYA YEKEEGEFAL
KTSKNAQVQS KHKSVKSKYT NGLLQVNYRH PKGTTPISIQ QDTTDLLVLV AGYDSATKWW
APIVDKDSQQ RVLVHGPYLV RSARIQGSTL SLRADIDETT DIQIVAPDSV TQFEWNGKAV
ELTKSKEGIW QGKLKFTQPK VEYTDLSKAK WQYQQGSPES EPDFDDSDWI KADHLETNSI
TPHVTYPVLF ADDYGFHTGS LWFRGTFNGS DAITGFNLTA NTGTASAWVA WLNGKYLGGF
ESGNQAFTDL GDTLKSDGEN VISLLVWTVG NADDWNANDA YKEARGFTMA QLLGVSNQTI
WSIDWKVQGN LGGEDLADPV RGPYNEGGLY GERKGWHLPD FETDDAWKTA SVPESKNRSG
VSWYRTEFEV NVPEGYDVPM GLRFKDKTDH RYRALVFLNG WQLGRYANDL GPQELYYLPE
GILNTSGKNT LALAVIPLDE AAQVGEVVLE PYGVLQSAKP KVDLVESPGY DKSKRG
//
