ID   A0A1X2H998_SYNRA        Unreviewed;       426 AA.
AC   A0A1X2H998;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Polymerase/histidinol phosphatase-like protein {ECO:0000313|EMBL:ORY95246.1};
GN   ORFNames=BCR43DRAFT_492680 {ECO:0000313|EMBL:ORY95246.1};
OS   Syncephalastrum racemosum (Filamentous fungus).
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Syncephalastraceae; Syncephalastrum.
OX   NCBI_TaxID=13706 {ECO:0000313|EMBL:ORY95246.1, ECO:0000313|Proteomes:UP000242180};
RN   [1] {ECO:0000313|EMBL:ORY95246.1, ECO:0000313|Proteomes:UP000242180}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 2496 {ECO:0000313|EMBL:ORY95246.1,
RC   ECO:0000313|Proteomes:UP000242180};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY95246.1}.
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DR   EMBL; MCGN01000006; ORY95246.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X2H998; -.
DR   InParanoid; A0A1X2H998; -.
DR   OMA; ANGYNAV; -.
DR   OrthoDB; 8377at2759; -.
DR   Proteomes; UP000242180; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR004013; PHP_dom.
DR   InterPro; IPR003141; Pol/His_phosphatase_N.
DR   InterPro; IPR016195; Pol/histidinol_Pase-like.
DR   PANTHER; PTHR42924; EXONUCLEASE; 1.
DR   PANTHER; PTHR42924:SF3; POLIIIAC DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02811; PHP; 1.
DR   SMART; SM00481; POLIIIAc; 1.
DR   SUPFAM; SSF89550; PHP domain-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242180};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        59..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        391..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          124..192
FT                   /note="Polymerase/histidinol phosphatase N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00481"
SQ   SEQUENCE   426 AA;  48141 MW;  15A0FB0D1C3043B7 CRC64;
     MQTDELDKKK TGSIALPIHD DVTAESSRSA STHYFDSRET SYEQERGRVR HYLHCAKPYL
     LGFSVRVAGL IVLLAVLIGL GLGLRYTEGM PRPEDDSNLV FDWRVDPASY LTPFNQSFQY
     NVLLDGHAHS TYSDGRMNVR QLLEWHIANG YNAVIVTDHN TIQGGLAAEK LALEEYADNI
     TVIPGIEYSC CRIHMNLIDI NESIPIGPPE PTDQELQQVI QRVHELGGLV IVNHIPWSNT
     TQDGYDLPRL PNHPSVEDLI SWGVDGFEVV HADTFDYATY LATVKHNLIQ MVGTDVHYPT
     TPATAWLAVQ AETKTRSGIM QAIRARRTSF LADPAGTRQQ VYPPSSAAYD RLLPLTGLGS
     YFSMFYTESK GMYSFQGTFC QPHRMQVHGN IIGWFIFWII VGLAVYELVR AFIRWVTERL
     RLRFFA
//