ID   A0A1X2HFY1_SYNRA        Unreviewed;       404 AA.
AC   A0A1X2HFY1;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=VHS domain-containing protein {ECO:0000259|PROSITE:PS50179};
GN   ORFNames=BCR43DRAFT_490401 {ECO:0000313|EMBL:ORY97812.1};
OS   Syncephalastrum racemosum (Filamentous fungus).
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Syncephalastraceae; Syncephalastrum.
OX   NCBI_TaxID=13706 {ECO:0000313|EMBL:ORY97812.1, ECO:0000313|Proteomes:UP000242180};
RN   [1] {ECO:0000313|EMBL:ORY97812.1, ECO:0000313|Proteomes:UP000242180}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 2496 {ECO:0000313|EMBL:ORY97812.1,
RC   ECO:0000313|Proteomes:UP000242180};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORY97812.1}.
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DR   EMBL; MCGN01000004; ORY97812.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X2HFY1; -.
DR   STRING; 13706.A0A1X2HFY1; -.
DR   InParanoid; A0A1X2HFY1; -.
DR   OMA; YGSVHRQ; -.
DR   OrthoDB; 922060at2759; -.
DR   Proteomes; UP000242180; Unassembled WGS sequence.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR   GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProt.
DR   GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR   CDD; cd14232; GAT_LSB5; 1.
DR   CDD; cd16980; VHS_Lsb5; 1.
DR   Gene3D; 1.20.58.160; -; 1.
DR   Gene3D; 1.25.40.90; -; 1.
DR   InterPro; IPR008942; ENTH_VHS.
DR   InterPro; IPR044103; GAT_LSB5.
DR   InterPro; IPR038425; GAT_sf.
DR   InterPro; IPR045007; LSB5.
DR   InterPro; IPR002014; VHS_dom.
DR   PANTHER; PTHR47789; LAS SEVENTEEN-BINDING PROTEIN 5; 1.
DR   PANTHER; PTHR47789:SF1; LAS SEVENTEEN-BINDING PROTEIN 5; 1.
DR   Pfam; PF00790; VHS; 1.
DR   SMART; SM00288; VHS; 1.
DR   SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR   SUPFAM; SSF89009; GAT-like domain; 1.
DR   PROSITE; PS50179; VHS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000242180}.
FT   DOMAIN          27..148
FT                   /note="VHS"
FT                   /evidence="ECO:0000259|PROSITE:PS50179"
FT   REGION          146..213
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          321..404
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        153..168
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        169..206
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        324..353
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        355..382
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        389..404
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   404 AA;  45575 MW;  F4FAA98C5E7202FA CRC64;
     MGIFSEEVQK TSVTFYIERL SNYEEIDWYI FQQLTESIMM QESGAYEAIE ATRKRLKHGT
     SQQKLRVIEV LRLLMENTNQ KFRRQLVSND KMKERLEMIF SSTAEDMKVR KELLSMVGAC
     AAKYRNEPGM HALRDLYDLG RTKLGVGPAK QRSRSGSVGT SAQPRRSPEA TPTMPPRPVQ
     TTPPPTKPQK RMSMPPANPP PPTKTKPRSS STAGANRRFN LEAAKPKIIQ EVALANQNWN
     NLVNALKFIN TSEDRWEIDL QHDARLQGYK ERCEESKKKI VRYARLVEDE EWIGTLLATN
     EELLRALEMY ETMAVGEVPQ NIPATTASPP PQSPSRPSSP HTRSPPPPPV RPYDDSTSSA
     IQDLADLRLS SPQATSSGQE NDPFADPFAD PIEEGHDNNN KRFG
//