ID A0A1X2I0L8_9FUNG Unreviewed; 375 AA.
AC A0A1X2I0L8;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Interferon-inducible GTPase-domain-containing protein {ECO:0000313|EMBL:ORZ06722.1};
GN ORFNames=BCR42DRAFT_427087 {ECO:0000313|EMBL:ORZ06722.1};
OS Absidia repens.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Cunninghamellaceae; Absidia.
OX NCBI_TaxID=90262 {ECO:0000313|EMBL:ORZ06722.1, ECO:0000313|Proteomes:UP000193560};
RN [1] {ECO:0000313|EMBL:ORZ06722.1, ECO:0000313|Proteomes:UP000193560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1336 {ECO:0000313|EMBL:ORZ06722.1,
RC ECO:0000313|Proteomes:UP000193560};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. IRG family. {ECO:0000256|ARBA:ARBA00005429}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORZ06722.1}.
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DR EMBL; MCGE01000038; ORZ06722.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X2I0L8; -.
DR STRING; 90262.A0A1X2I0L8; -.
DR OrthoDB; 1352701at2759; -.
DR Proteomes; UP000193560; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030385; G_IRG_dom.
DR InterPro; IPR007743; Immunity-related_GTPase-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR32341; INTERFERON-INDUCIBLE GTPASE; 1.
DR PANTHER; PTHR32341:SF10; INTERFERON-INDUCIBLE GTPASE 5; 1.
DR Pfam; PF05049; IIGP; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51716; G_IRG; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000193560};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 117..343
FT /note="IRG-type G"
FT /evidence="ECO:0000259|PROSITE:PS51716"
SQ SEQUENCE 375 AA; 41831 MW; 3787B2DE771CC39E CRC64;
MGQATSKNLR PDAFYDYKDV GNKFTKVTLS TLAVPMVIIA FPLLNAYTFT EEELTGFKVM
DGAIGGLLGV IGWPLAPFLA CYGVFQVMFK EGPTEPLPIP KHIKDAARRS IGLNCEQFYN
VAVVGVSGTG KSSVVNGILG YRDHDKDAAA TGESETTKKP RAYRHPDLRS MVLWDMPGAN
TMNHPGGTYF EDKFLCAFDS LIIVTAERLM ETDIQIAKQA QLCQIPILIV RNKADQAIGA
KIRKLQHAYE DEQVNRSASQ PRTATTILPS AIHPKNSNNK GDGDMDKDKI WAQACGQLGK
EVRKSIYRQM KDNKLSTKRL FTISAWNLQE FVHVLSHKQL DSNLKLIDEQ RFLRVLIEGV
ILKRKRELTK TTGTQ
//
