ID   A0A1X2I537_9FUNG        Unreviewed;       437 AA.
AC   A0A1X2I537;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Putative RNA methylase family UPF0020-domain-containing protein {ECO:0000313|EMBL:ORZ09466.1};
GN   ORFNames=BCR42DRAFT_381538 {ECO:0000313|EMBL:ORZ09466.1};
OS   Absidia repens.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Cunninghamellaceae; Absidia.
OX   NCBI_TaxID=90262 {ECO:0000313|EMBL:ORZ09466.1, ECO:0000313|Proteomes:UP000193560};
RN   [1] {ECO:0000313|EMBL:ORZ09466.1, ECO:0000313|Proteomes:UP000193560}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 1336 {ECO:0000313|EMBL:ORZ09466.1,
RC   ECO:0000313|Proteomes:UP000193560};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORZ09466.1}.
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DR   EMBL; MCGE01000027; ORZ09466.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X2I537; -.
DR   STRING; 90262.A0A1X2I537; -.
DR   OrthoDB; 1364859at2759; -.
DR   Proteomes; UP000193560; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR   GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR000241; RlmKL-like_Mtase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR14911; THUMP DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR14911:SF13; TRNA (GUANINE(6)-N2)-METHYLTRANSFERASE THUMP3; 1.
DR   Pfam; PF01170; UPF0020; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:ORZ09466.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193560};
KW   Transferase {ECO:0000313|EMBL:ORZ09466.1}.
FT   DOMAIN          256..405
FT                   /note="UPF0020"
FT                   /evidence="ECO:0000259|Pfam:PF01170"
FT   REGION          203..228
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..228
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   437 AA;  49245 MW;  BE53BDEA3847AE41 CRC64;
     MSRPTIHILF HVPEGLEQIA IIDLKETILQ FEHADPLATA FIGEARTGRV HMFSKLQQHD
     DTILWIQYLT TTTLLSVYHM TIITKTTTLP NAVYHSGQDS EVLGEHIFSV VKEAPWSDYI
     SVLKTKDNDT SATSTTFRAT FYKDQLQHGV KSQVISGWMG YAYSQIFPDW KVNLKTYDYD
     VVGVWGRTRD TALLGHFGLE DSTDDDDMVD NNSNTDGTEQ QQQDQMNDQQ IELSEPKTIL
     LYIGLNIPIP DSKYRNRVHL GRTSLNPPIA YCLTRLANPL PGQIIMDMCC GTGTIPIEGA
     GKYPDTLWIG GEVKVKTLCL KAKGNMQHAG IHNIEFLLSD GRRLNFRREC VDTVISDWPW
     GMREGSYSTI QKLYPKFMRE IGQVLCVGGK AYIVSQGNKL MRTVLDYGWV KNLFSLEEIL
     PIAIGGVGVS VYVLIKK
//