ID A0A1X2I5G4_9FUNG Unreviewed; 718 AA.
AC A0A1X2I5G4;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};
GN ORFNames=BCR42DRAFT_120375 {ECO:0000313|EMBL:ORZ09596.1};
OS Absidia repens.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Cunninghamellaceae; Absidia.
OX NCBI_TaxID=90262 {ECO:0000313|EMBL:ORZ09596.1, ECO:0000313|Proteomes:UP000193560};
RN [1] {ECO:0000313|EMBL:ORZ09596.1, ECO:0000313|Proteomes:UP000193560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1336 {ECO:0000313|EMBL:ORZ09596.1,
RC ECO:0000313|Proteomes:UP000193560};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the initiation of assembly of the COPII coat
CC required for the formation of transport vesicles from the endoplasmic
CC reticulum (ER) and the selection of cargo molecules. Also involved in
CC autophagy. {ECO:0000256|ARBA:ARBA00024687,
CC ECO:0000256|RuleBase:RU364101}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|RuleBase:RU364101}.
CC -!- SIMILARITY: Belongs to the SEC16 family.
CC {ECO:0000256|ARBA:ARBA00005927, ECO:0000256|RuleBase:RU364101}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORZ09596.1}.
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DR EMBL; MCGE01000027; ORZ09596.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X2I5G4; -.
DR STRING; 90262.A0A1X2I5G4; -.
DR OrthoDB; 1361743at2759; -.
DR Proteomes; UP000193560; Unassembled WGS sequence.
DR GO; GO:0070971; C:endoplasmic reticulum exit site; IEA:UniProt.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR GO; GO:0048208; P:COPII vesicle coating; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.1030; -; 1.
DR InterPro; IPR024298; ACE1_Sec16_Sec31.
DR InterPro; IPR024880; Sec16.
DR InterPro; IPR024340; Sec16_CCD.
DR PANTHER; PTHR13402; RGPR-RELATED; 1.
DR PANTHER; PTHR13402:SF6; SECRETORY 16, ISOFORM I; 1.
DR Pfam; PF12932; Sec16; 1.
DR Pfam; PF12931; Sec16_C; 1.
PE 3: Inferred from homology;
KW Autophagy {ECO:0000256|RuleBase:RU364101};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW ECO:0000256|RuleBase:RU364101};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892,
KW ECO:0000256|RuleBase:RU364101}; Membrane {ECO:0000256|RuleBase:RU364101};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU364101};
KW Reference proteome {ECO:0000313|Proteomes:UP000193560};
KW Transport {ECO:0000256|RuleBase:RU364101}.
FT DOMAIN 374..500
FT /note="Sec16 central conserved"
FT /evidence="ECO:0000259|Pfam:PF12932"
FT DOMAIN 557..717
FT /note="Ancestral coatomer element 1 Sec16/Sec31"
FT /evidence="ECO:0000259|Pfam:PF12931"
FT REGION 209..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..330
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 718 AA; 77960 MW; 85D09039EF98DA65 CRC64;
MAQDQPVVAN AITQNEELNS QGTGLLEQVN KGDGNTTNGV LLGLDNKDAV SLSTDIPQTA
VANQKWDQVD MDSQNEVLPA SQTGDQQSAL HSDSIDVVKG LGDDLDDLIL GDTRQSNQAP
PSTAASTFTQ NIYNPISRTT TPQLPTEPTI TCFNPSCQTV NKSSSKFCEE CGTPFVTNGS
RAPTPAIPTS QQVAPAPAAT PVYDPSLYSP TYSPSIPENQ YSPAATSTSV YEPQQQQQQQ
QQHHIGSIHQ SAQIYNTQTA TPVYNEPQPY ISRTVTPVYN PLSSSTPGRD SSIYSAQQSQ
PVYPSTTTST SVYDPSSYYG TNNNTTPVPP PIANQQQPYS SDPYVATATT APPISATVQQ
PPVDQDPLQR YKGCPLVQFG FGGKLCMMFP RADMQYGYGG GVSAKKSPGA IQIKMMKDIA
SVSSTVGDDS NQLSYLQSFI GPVLLDPDYS TKNKKKQVIT YMEQRILEME NTPMTTNGPS
DAGVRVLLWK IVKLMIEQDG LPESDTTNMA ILGLLQPQKT TAVEDVNNFS VPAYGGTEQV
QNGDQDVNVS EVVLDKLQDY LSVGDRRGAV NYAIQEDLWS HALIISSCVD RDLWQSVVRG
FTQRDLAAPP GGRLTRNYHH VDGNRQGLRV LYALFSGLGA SSMSEFFVSN NQPQHTMGDN
ADGPGLNPSL PLRNDELAKW QETLGLMYAN RTTKDFEAMT ALGDILKNQG WINASHIW
//
