ID A0A1X2IF96_9FUNG Unreviewed; 985 AA.
AC A0A1X2IF96;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 13-SEP-2023, entry version 26.
DE RecName: Full=RhoGEF domain-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BCR42DRAFT_51753 {ECO:0000313|EMBL:ORZ15329.1};
OS Absidia repens.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Cunninghamellaceae; Absidia.
OX NCBI_TaxID=90262 {ECO:0000313|EMBL:ORZ15329.1, ECO:0000313|Proteomes:UP000193560};
RN [1] {ECO:0000313|EMBL:ORZ15329.1, ECO:0000313|Proteomes:UP000193560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1336 {ECO:0000313|EMBL:ORZ15329.1,
RC ECO:0000313|Proteomes:UP000193560};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORZ15329.1}.
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DR EMBL; MCGE01000013; ORZ15329.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X2IF96; -.
DR STRING; 90262.A0A1X2IF96; -.
DR OrthoDB; 23973at2759; -.
DR Proteomes; UP000193560; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd00014; CH_SF; 1.
DR CDD; cd05992; PB1; 1.
DR CDD; cd13246; PH_Scd1; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010481; Cdc24/Scd1_N.
DR InterPro; IPR033511; Cdc24/Scd1_PH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR47339; CELL DIVISION CONTROL PROTEIN 24; 1.
DR PANTHER; PTHR47339:SF1; CELL DIVISION CONTROL PROTEIN 24; 1.
DR Pfam; PF06395; CDC24; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF15411; PH_10; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00666; PB1; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS51745; PB1; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000193560}.
FT DOMAIN 239..413
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 437..555
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 900..985
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 781..837
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 682..700
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 711..754
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 798..812
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 813..828
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 985 AA; 111294 MW; 5514B2D20C95B5EA CRC64;
MASTTLQRRT PSLGALSTIT PPHSQHSTPS LAPTTSSNTP PPGTSLYHTC RLVLDKLAFV
PGMSCWLDME EDNLSPSLSP INTSSPPLMP LSTTSPALTA ASTSTADSAI TTTSCSTNNF
NSDPLSKLCY LCRRGTPLFT LFNALNTNQP LKMDPNPKLN QVNNCKANVY HFLVACRKQL
LFPEEELFAV SDLYVDDTNG FVKVVNTVLK ILQLLEDKGI ISSQCASRDS CPMVPPKDIR
DQVVFELLST ERKYVQDLET LQTYMRELQQ QRILSQDTVH YLFGNLNALV DFQRRFLIEM
EKTAENQPQD QHFGLLFSQM EGAFSVYEPY CSNFYSAQDL VVQEAPKLQK LNIMNPTHQL
TSLLIKPIQR ICKYPLLLNE LIKSTNKEWS ITLSEMADGL DTMRRVADKV NETQRKHENL
QMVVELKRRV DDWKGISIDK CGQLLLQDKM VVSAYDNERE MHIFFFENRL LLCKECKDNN
KNRNTITIKK RRRGTLEPKG KIETSMITCI HNISKNGEWA LMIEWKEQDV EKFILKFRNE
EQYKLWESTL NKQKGFQSTP SISSSSNNHV SGINSTMPTS LPLPQLLSSN DNWSFIDPDD
EEDEVDFIED DGDYHGSGAR SRSNSFSAHI LNTFSTRPKS SRNNSTDMSA MKSLTVNATT
GRPNTPGLNL QPLPRSNHGI PIHQHDVSQQ PSSGDYFFYP SSPPPSNPSS PTSSSRVSPN
NSSSGRSFRD HTSSSSQQLH HHYLQQQQQH YSTKGLPMPR EPMTPAMDYF TIPTIDNFDA
VVGRPGPSLS ERHQYQQHQH HNNHHHRKQM PPPTRSRAQS SPIIQSSESH IRRDGGGMTR
FMDKSATWEQ YTHQPTTAPL PRLSDKKSSV SLHSQMDHIL ISSVSTTATA TATTTAPVSP
GQLKVKMIYN DGAFSLVIPQ HISYIELMER VEQKLHAMID LRPGTSFRLK YRDEEGDFIT
MSSTEDVQMA FDGYQHSGAR LYVFL
//
