ID A0A1X2IXY5_9FUNG Unreviewed; 844 AA.
AC A0A1X2IXY5;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Elongation factor 2 {ECO:0000256|ARBA:ARBA00017891};
GN ORFNames=BCR42DRAFT_365323 {ECO:0000313|EMBL:ORZ24150.1};
OS Absidia repens.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Cunninghamellaceae; Absidia.
OX NCBI_TaxID=90262 {ECO:0000313|EMBL:ORZ24150.1, ECO:0000313|Proteomes:UP000193560};
RN [1] {ECO:0000313|EMBL:ORZ24150.1, ECO:0000313|Proteomes:UP000193560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1336 {ECO:0000313|EMBL:ORZ24150.1,
RC ECO:0000313|Proteomes:UP000193560};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORZ24150.1}.
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DR EMBL; MCGE01000002; ORZ24150.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X2IXY5; -.
DR STRING; 90262.A0A1X2IXY5; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000193560; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01681; aeEF2_snRNP_like_IV; 1.
DR CDD; cd04096; eEF2_snRNP_like_C; 1.
DR CDD; cd01885; EF2; 1.
DR CDD; cd16261; EF2_snRNP_III; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF10; ELONGATION FACTOR 2; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:ORZ24150.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000193560}.
FT DOMAIN 17..255
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 844 AA; 93550 MW; 22F1DF0D9E2642ED CRC64;
MGNFTVDEIR GLMDKVTNVR NMSVIAHVDH GKSTLSDSLV SKAGIISAGR AGETRFMDTR
QDEQDRGITI KSTAISLYFQ LPDPEDIKEI KGQITNGSDF LINMIDSPGH VDFSSEVTAA
LRVTDGALVV VDCIDGVCVQ TETVLRQALG ERIKPIVVIN KVDRALLELQ LGKEELYNAF
ARTIESVNVI IATYLDEELG DVQVHPEKGT VAFASALHGW GFTLRQFAQR YSKKFGVDKE
KMMVKLWGEN YFNPKTKKWT TKSNDADGKP LERAFNMFIL DPIYKIFDSV MNFKKDQVTT
LLEKLDIQLK ADEKDLEGKA LLKVVMRKFL PCGDALLEMI CIHLPSPITS QRYRVPNLYE
GPADDECALG IRDCNPQGPL MLYISKMVPT SDKGRFYAFG RVFSGTVRAG MKVRIQGPNF
IPGTKTDLHI KSVQRTVLMM GRGVEAIDDC PAGNIIGLVG VDQFLVKSGT ITTSETAHNM
KVMKFSVSPV VQVAVEVKNA NDLPKLVEGL KRLSKSDPCV LTYTSESGEH IVAGAGELHL
EICLKDLEED HAQVPLKTGD PVVQYRETVT AESSIDCLSK SPNKHNRIYM RALPLDDELS
NAIEAGKVGP KDDFKARARI LADQFNWDVT EARKIWCFGP DATGPNLMVD VTKAVQYLNE
IKDSCVAAFQ WATKEGPLAE ENLRGCRFNI LDVTLHADAI HRGGGQIIPT CRRVVYASVL
TAAPGIQEPM YLVEVQCPES AIGGIYSVLN RRRGIVFSEE QRPGTPMMNI KAYLPVNESF
GFNSDLRAAT SGQAFPQAVF DHWQAMTGDP LEAGNKVYDI IRNVRKRKGL VEDIPGLDRY
YDKL
//
