ID   A0A1X2IYZ0_9FUNG        Unreviewed;       507 AA.
AC   A0A1X2IYZ0;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Dbl homology domain-containing protein {ECO:0000313|EMBL:ORZ24510.1};
GN   ORFNames=BCR42DRAFT_91970 {ECO:0000313|EMBL:ORZ24510.1};
OS   Absidia repens.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Cunninghamellaceae; Absidia.
OX   NCBI_TaxID=90262 {ECO:0000313|EMBL:ORZ24510.1, ECO:0000313|Proteomes:UP000193560};
RN   [1] {ECO:0000313|EMBL:ORZ24510.1, ECO:0000313|Proteomes:UP000193560}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 1336 {ECO:0000313|EMBL:ORZ24510.1,
RC   ECO:0000313|Proteomes:UP000193560};
RG   DOE Joint Genome Institute;
RA   Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA   Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA   Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA   Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA   Visel A., Grigoriev I.V.;
RT   "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORZ24510.1}.
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DR   EMBL; MCGE01000002; ORZ24510.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X2IYZ0; -.
DR   STRING; 90262.A0A1X2IYZ0; -.
DR   OrthoDB; 1358804at2759; -.
DR   Proteomes; UP000193560; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:2000431; P:regulation of cytokinesis, actomyosin contractile ring assembly; IEA:InterPro.
DR   Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000219; DH-domain.
DR   InterPro; IPR026817; Ect2.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR16777; PROTEIN ECT2; 1.
DR   PANTHER; PTHR16777:SF2; PROTEIN ECT2; 1.
DR   Pfam; PF00621; RhoGEF; 1.
DR   SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50010; DH_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000193560}.
FT   DOMAIN          84..255
FT                   /note="DH"
FT                   /evidence="ECO:0000259|PROSITE:PS50010"
FT   REGION          389..428
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   507 AA;  58039 MW;  5930AC38719545E0 CRC64;
     MNNDGEKHQY EQQLGHLLEL SSISPISDIG STSTSSSIHS ASYYTEQLMD DLSIIDDIYS
     SYDHEQLTLA INNQVTYSTR NGALKEQMVQ HLIKTESQFV HDLDAFHTHF AAEMPQFQVQ
     KNKLAFQTTD CDILFKPTLD LISAHQVLLD ELRQRLSIYG PTQIISDIFL QFFDHTNASY
     TAYLKGFSST LLTLDRLHKT NAFIKFCESR QQSNPSLKDC GYYICIPLIR LSAYTQAVDQ
     CTQLTEPAHP DYNALITISK RYKTREQQWQ SLVEDCLSHY KVYKWFRAVQ NSPALVTPTR
     RLLLYSDLIH LDPDAPTDMT DHRTYILYND LLIFCKQQKD GRMFYQGIVI LDKAVLKPMD
     RKIANKIRDK HQKAIKQANG SRKLSLFGIK KQQQQQPQQQ QQLKSNSSNQ TSTRTSTTSD
     SSSSGSASSI YSEDSGVYGF EIFFQFVMDK NVTSYTNPIT SYGMGPVTSV ASNDSVRRHI
     LLTRSLEEQT LWNEHLQRVI KSVTSSR
//