ID A0A1X2M0X6_9MYCO Unreviewed; 458 AA.
AC A0A1X2M0X6;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Urea transporter {ECO:0000313|EMBL:OSC42701.1};
GN ORFNames=B8W66_03970 {ECO:0000313|EMBL:OSC42701.1};
OS Mycobacterium decipiens.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1430326 {ECO:0000313|EMBL:OSC42701.1, ECO:0000313|Proteomes:UP000193247};
RN [1] {ECO:0000313|EMBL:OSC42701.1, ECO:0000313|Proteomes:UP000193247}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TBL 1200985 {ECO:0000313|EMBL:OSC42701.1,
RC ECO:0000313|Proteomes:UP000193247};
RA Tortoli E., Trovato A., Cirillo D.M.;
RT "The new phylogeny of genus Mycobacterium.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the urea transporter family.
CC {ECO:0000256|ARBA:ARBA00005914}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OSC42701.1}.
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DR EMBL; NCXP01000002; OSC42701.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X2M0X6; -.
DR STRING; 1430326.B8W66_03970; -.
DR OrthoDB; 9801227at2; -.
DR Proteomes; UP000193247; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015204; F:urea transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR029020; Ammonium/urea_transptr.
DR InterPro; IPR025979; ChrR-like_cupin_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR InterPro; IPR004937; Urea_transporter.
DR PANTHER; PTHR10464; UREA TRANSPORTER; 1.
DR PANTHER; PTHR10464:SF4; UREA TRANSPORTER; 1.
DR Pfam; PF12973; Cupin_7; 1.
DR Pfam; PF03253; UT; 1.
DR SUPFAM; SSF51182; RmlC-like cupins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 45..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 362..445
FT /note="ChrR-like cupin"
FT /evidence="ECO:0000259|Pfam:PF12973"
FT REGION 319..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 458 AA; 48855 MW; 6E5C758BEEAA9D6F CRC64;
MERPVKPPLD DTCSRVETSE VVPYYRLVLR GCSQLCFQSN ALTGLFFLAA VVVASPIAAT
YFLVAAIIAP AGRMLLGERG PVLATGLPGL NPCLIALSLP AFFQTSWTNV GMWVVLVVCV
AIAVVLVRLL VAALPFPILA LPFLIIFWGL YALAPHLDVL RPAASRPPEV TAFHPVSAVL
FSLGQAVFSP SIWSGLLFLA GILISSWRHA VLALLGAAIG TAVSYYYGDV HPMGVNFGLY
GFNGVLTAVA VYTICGGMLR LALLGALVAT ILTPAIAAIG LQTVSAPFVF TTWFVLALGW
IEQKWFDVPA LAAEGVPMAK SSGSSGNEHN PQGDTHMSSP PDSIVFSNLL EQVKNLNATG
EWTAFRPGVT AHWLYNDGNG GPAAVFLRYT PGARVAEHEH MGYEHLLILE GDQFDEHGSY
PQGSFVINPP GTRHSPGSVG GCVALLIYEK AVRFLCEE
//
