ID A0A1X3D675_9NEIS Unreviewed; 382 AA.
AC A0A1X3D675;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Citrate synthase {ECO:0000256|PIRNR:PIRNR001369};
GN ORFNames=BWD09_08965 {ECO:0000313|EMBL:OSI15306.1};
OS Neisseria dentiae.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=194197 {ECO:0000313|EMBL:OSI15306.1, ECO:0000313|Proteomes:UP000193118};
RN [1] {ECO:0000313|Proteomes:UP000193118}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19151 {ECO:0000313|Proteomes:UP000193118};
RA Wolfgang W.J., Cole J., Wroblewski D., Mcginnis J., Musser K.A.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+);
CC Xref=Rhea:RHEA:16845, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57288; EC=2.3.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00000308};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate
CC from oxaloacetate: step 1/2. {ECO:0000256|ARBA:ARBA00004751}.
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|PIRNR:PIRNR001369,
CC ECO:0000256|RuleBase:RU003406}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OSI15306.1}.
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DR EMBL; MTBO01000024; OSI15306.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X3D675; -.
DR STRING; 194197.BWD09_08965; -.
DR UniPathway; UPA00223; UER00717.
DR Proteomes; UP000193118; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0036440; F:citrate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR CDD; cd06117; Ec2MCS_like_1; 1.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR011278; 2-MeCitrate/Citrate_synth_II.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR019810; Citrate_synthase_AS.
DR InterPro; IPR024176; Citrate_synthase_bac-typ.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR NCBIfam; TIGR01800; cit_synth_II; 1.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF25; CITRATE SYNTHASE-RELATED PROTEIN DDB_G0287281; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PIRSF; PIRSF001369; Citrate_synth; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000193118};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR001369}.
FT ACT_SITE 268
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
FT ACT_SITE 319
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
SQ SEQUENCE 382 AA; 42637 MW; AF257AD7B5D72C3C CRC64;
MTTETPTFKP KKSVALSGVP AGNTALCTVG RSGNDLSYRG YDILDLAEHC EFEEVAHLLI
HDHLPNKFEL AAYKKKLQSL RGLPIRVIQV LESLPAHTHP MDVLRTGVSM LGCVHPERES
QPASEARDIA DKLIACLGSM LLYWYQFSHN GKRIKVESKE DSIGGHFLHL LHGKRPSKSH
IKAMHVSLIL YAEHEFNAST FTSRVIAGTG SDIYSCITGA IGALKGPKHG GANEVAYDIQ
KRYRSADEAE ADIRERIGRK EIVIGFGHPV YTVSDPRNVV IKEVARELSA ETGDMRLFDI
AERLETLMWN EKKMFPNLDW FSAVSYQKLG VPTAMFTPLF VISRTTGWSA HVLEQRQDGK
IIRPSANYTG PDDLPFVPME ER
//
