ID   A0A1X4J0Y4_9RHOB        Unreviewed;       345 AA.
AC   A0A1X4J0Y4;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Cell shape-determining protein MreB {ECO:0000256|HAMAP-Rule:MF_02207};
GN   Name=mreB {ECO:0000256|HAMAP-Rule:MF_02207};
GN   ORFNames=BV911_03155 {ECO:0000313|EMBL:OSP56300.1};
OS   Pseudoruegeria sp. SK021.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Pseudoruegeria.
OX   NCBI_TaxID=1933035 {ECO:0000313|EMBL:OSP56300.1, ECO:0000313|Proteomes:UP000194129};
RN   [1] {ECO:0000313|EMBL:OSP56300.1, ECO:0000313|Proteomes:UP000194129}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SK021 {ECO:0000313|EMBL:OSP56300.1,
RC   ECO:0000313|Proteomes:UP000194129};
RA   Pohlner M., Marshall I., Schreiber L., Cypionka H., Engelen B.;
RT   "Draft genome sequence of Pseudoruegeria str. SK021, a representative of
RT   the marine Rosebacter group, isolated from North Sea sediment.";
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Forms membrane-associated dynamic filaments that are
CC       essential for cell shape determination. Acts by regulating cell wall
CC       synthesis and cell elongation, and thus cell shape. A feedback loop
CC       between cell geometry and MreB localization may maintain elongated cell
CC       shape by targeting cell wall growth to regions of negative cell wall
CC       curvature. {ECO:0000256|HAMAP-Rule:MF_02207}.
CC   -!- SUBUNIT: Forms polymers. {ECO:0000256|HAMAP-Rule:MF_02207}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_02207}.
CC       Note=Membrane-associated. {ECO:0000256|HAMAP-Rule:MF_02207}.
CC   -!- SIMILARITY: Belongs to the FtsA/MreB family.
CC       {ECO:0000256|ARBA:ARBA00023458, ECO:0000256|HAMAP-Rule:MF_02207}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OSP56300.1}.
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DR   EMBL; MTBG01000002; OSP56300.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X4J0Y4; -.
DR   STRING; 1933035.BV911_03155; -.
DR   OrthoDB; 9768127at2; -.
DR   Proteomes; UP000194129; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-UniRule.
DR   CDD; cd10225; MreB_like; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   HAMAP; MF_02207; MreB; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR004753; MreB.
DR   NCBIfam; TIGR00904; mreB; 1.
DR   PANTHER; PTHR42749; CELL SHAPE-DETERMINING PROTEIN MREB; 1.
DR   PANTHER; PTHR42749:SF1; CELL SHAPE-DETERMINING PROTEIN MREB; 1.
DR   Pfam; PF06723; MreB_Mbl; 1.
DR   PRINTS; PR01652; SHAPEPROTEIN.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_02207};
KW   Cell shape {ECO:0000256|ARBA:ARBA00022960, ECO:0000256|HAMAP-
KW   Rule:MF_02207}; Cytoplasm {ECO:0000256|HAMAP-Rule:MF_02207};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_02207};
KW   Reference proteome {ECO:0000313|Proteomes:UP000194129}.
FT   BINDING         18..20
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_02207"
FT   BINDING         164..166
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_02207"
FT   BINDING         212..215
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_02207"
FT   BINDING         294..297
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_02207"
SQ   SEQUENCE   345 AA;  36682 MW;  2D07530EC6B6EE5C CRC64;
     MRLFSGLFSA DMAIDLGTAN TLVYIRGKGI VLNEPSVVAY HVKDGVKTVL AVGEDAKLML
     GRTPGSIEAI RPMREGVIAD FDVAEEMIKH FIRKVHRRTS LSKPKIIVCV PHGATPVEKR
     AIRQSVLSAG ARRAGLIAEP IAAAIGAGMP ITDPTGNMVV DIGGGTTEVA VLSLGDIVYA
     RSVRVGGDRM DEGIISYLRR QHNLLIGEAT AERIKTSIGT ARMPDDGRGQ ALMIRGRDLL
     NGVPKETEIT QAQVAEALAE PVQQICEAVM IALEATPPDL AADIVDRGVM LTGGGALLGD
     LDLALREQTG LAITVADEPL RCVAIGTGKA LEFENQLRHV IDYDS
//