ID A0A1X4N2U4_9PROT Unreviewed; 498 AA.
AC A0A1X4N2U4;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=methylmalonate-semialdehyde dehydrogenase (CoA acylating) {ECO:0000256|ARBA:ARBA00013048};
DE EC=1.2.1.27 {ECO:0000256|ARBA:ARBA00013048};
GN ORFNames=THS27_24635 {ECO:0000313|EMBL:OSQ35146.1};
OS Thalassospira sp. MCCC 1A01428.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Thalassospiraceae; Thalassospira.
OX NCBI_TaxID=1470575 {ECO:0000313|EMBL:OSQ35146.1, ECO:0000313|Proteomes:UP000193740};
RN [1] {ECO:0000313|EMBL:OSQ35146.1, ECO:0000313|Proteomes:UP000193740}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCCC 1A01428 {ECO:0000313|EMBL:OSQ35146.1,
RC ECO:0000313|Proteomes:UP000193740};
RA Lai Q., Shao Z.;
RT "The draft genome sequence of Thalassospira sp. MCCC 1A01428.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OSQ35146.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JFJZ01000073; OSQ35146.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X4N2U4; -.
DR STRING; 1470575.THS27_24635; -.
DR OrthoDB; 9772584at2; -.
DR Proteomes; UP000193740; Unassembled WGS sequence.
DR GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:InterPro.
DR CDD; cd07085; ALDH_F6_MMSDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010061; MeMal-semiAld_DH.
DR NCBIfam; TIGR01722; MMSDH; 1.
DR PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43866:SF4; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 15..478
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 498 AA; 52716 MW; 888577C08B2231D8 CRC64;
MKRIEHIIGG EHTSGESTRT GAIFNPATGE QTGEVVLASE ADVNTVVATA KAAFESWSAT
PPAKRAQVMF AYKGLLEKRA DEIASTISAE HGKTHPDALG EVARALEVVE FACGIPHLLK
GDFSRNVGTS VDACADRHAL GVVAGITPFN FPTMVPLWMI PMAIACGNTF VLKPSERDPS
AANLVVELLH EAGLPKGVCN VLHGDKVAVD GLLHHPDVQA ISFVGSTPIA EYVYKTGTAN
GKRVQALGGA KNHMIVMPDA DIDQAVDALM GAGYGAAGER CMAVSVAVPV GEETADRLVK
ALAPKVAALK IGPSTDTDAD MGPVITEAHK NKVLGYIDAG VKEGAELVVD GRGFKLQGYE
NGYFVGGSLF DRVTPDMSIY TDEIFGPVLS VVRADSYDTA VDLINKHEYG NGTAIFTRDG
DAARNFVDRI QVGMVGVNVP IPVPVGYHSF GGWKRSIFGS HGIYGPEAVH FYTKLKTVTM
RWPTGIRSGA EFNFPSNG
//
