ID A0A1X4N357_9PROT Unreviewed; 580 AA.
AC A0A1X4N357;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN ORFNames=THS27_23695 {ECO:0000313|EMBL:OSQ36200.1};
OS Thalassospira sp. MCCC 1A01428.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Thalassospiraceae; Thalassospira.
OX NCBI_TaxID=1470575 {ECO:0000313|EMBL:OSQ36200.1, ECO:0000313|Proteomes:UP000193740};
RN [1] {ECO:0000313|EMBL:OSQ36200.1, ECO:0000313|Proteomes:UP000193740}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCCC 1A01428 {ECO:0000313|EMBL:OSQ36200.1,
RC ECO:0000313|Proteomes:UP000193740};
RA Lai Q., Shao Z.;
RT "The draft genome sequence of Thalassospira sp. MCCC 1A01428.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OSQ36200.1}.
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DR EMBL; JFJZ01000060; OSQ36200.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X4N357; -.
DR STRING; 1470575.THS27_23695; -.
DR OrthoDB; 7374210at2; -.
DR Proteomes; UP000193740; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 123..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 417..530
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT REGION 88..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..244
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..270
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 580 AA; 63613 MW; B8E56B5D815DD989 CRC64;
MNQMVARKQI SYEIYIKDRM GKWVIHAHYT GAQKAIAEEE THQLEREQHV MAVKLIREVY
SSETNSADEY IVYQTRDAES REKIATSRAA HSIEQVADPA PDENNDTAPA AKTKSKPRKK
KDIGLIGLIL KLLLAFCGAI AIGLAVMLGS ARLLEYLPGM GYHISQGVFE KANFFAFVLG
FVVSITPMTM ALTRQFRSSS RSRKKDNTPD QAAVAPTIPS GPTDEQMRQA RAEALRRSLE
ENRAAASDET ASAPARPDED DSETTGQPEH PEPEKTPALQ ATRQIMRDFM AGSVIAISET
MPQMDAYHKF GINLYVAGAC DACSERNALP HDNGRTILRD CISALGANGK MSETFCNSVD
QYLLEPKYND MYGAGRDSML NFMKDENSIS VSVAHALTIW SEKPAPTTQQ PGKKIHALMF
TDIVNSTRLT QELGDTGAQQ MIHAHNKIVR TALLNNYGKE VKHMGDGIMA VFPSSNAAVE
GAIEIQRQMA RYNATGKLEF HVRIGINAGE ALAEENDLFG AVVQLAARVC AAATGDETLV
SPAVRETYAG KRATFTSRGA RTMKGFDTPI EVFAVTSRTK
//
