ID   A0A1X6MVM0_9APHY        Unreviewed;       917 AA.
AC   A0A1X6MVM0;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Zn-dependent exopeptidase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=POSPLADRAFT_1070696 {ECO:0000313|EMBL:OSX60408.1};
OS   Postia placenta MAD-698-R-SB12.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Postiaceae; Postia.
OX   NCBI_TaxID=670580 {ECO:0000313|EMBL:OSX60408.1, ECO:0000313|Proteomes:UP000194127};
RN   [1] {ECO:0000313|EMBL:OSX60408.1, ECO:0000313|Proteomes:UP000194127}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MAD-698-R-SB12 {ECO:0000313|EMBL:OSX60408.1,
RC   ECO:0000313|Proteomes:UP000194127};
RG   DOE Joint Genome Institute;
RA   Gaskell J., Kersten P., Larrondo L.F., Canessa P., Martinez D., Hibbett D.,
RA   Schmoll M., Kubicek C.P., Martinez A.T., Yadav J., Master E.,
RA   Magnuson J.K., James T., Yaver D., Berka R., Labutti K., Lipzen A.,
RA   Aerts A., Barry K., Henrissat B., Blanchette R., Grigoriev I., Cullen D.;
RT   "Genome Sequence of the Model Brown-Rot Fungus Postia placenta SB12.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC       {ECO:0000256|ARBA:ARBA00005634}.
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DR   EMBL; KZ110600; OSX60408.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X6MVM0; -.
DR   STRING; 670580.A0A1X6MVM0; -.
DR   OrthoDB; 67337at2759; -.
DR   Proteomes; UP000194127; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd08022; M28_PSMA_like; 1.
DR   CDD; cd02121; PA_GCPII_like; 1.
DR   Gene3D; 3.50.30.30; -; 1.
DR   Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR046450; PA_dom_sf.
DR   InterPro; IPR003137; PA_domain.
DR   InterPro; IPR007484; Peptidase_M28.
DR   InterPro; IPR039373; Peptidase_M28B.
DR   InterPro; IPR007365; TFR-like_dimer_dom.
DR   InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR   PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR   PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR   Pfam; PF02225; PA; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
DR   Pfam; PF04253; TFR_dimer; 1.
DR   SUPFAM; SSF52025; PA domain; 1.
DR   SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 2.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000194127};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        37..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          240..316
FT                   /note="PA"
FT                   /evidence="ECO:0000259|Pfam:PF02225"
FT   DOMAIN          404..544
FT                   /note="Peptidase M28"
FT                   /evidence="ECO:0000259|Pfam:PF04389"
FT   DOMAIN          830..914
FT                   /note="Transferrin receptor-like dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF04253"
SQ   SEQUENCE   917 AA;  101745 MW;  DAFC20F53C9F1C86 CRC64;
     MASEKLSMSF YDKQPHPIPA PVVATAPPTA RGNRAVFWRK LVVTSLAALS LLYYVGCWFC
     ALRQRIDAQE GRWIAQAFGA HPPRNLGYRR IPFGKAAEEI FLAVPNPASA IAASRQYATT
     PHLAGSPGDY RTATDFLALL QTELSIEAPT PLPVFSAGTA ESRNATLSIS EGLNGPTAWI
     DTYYPVMNTP LDRRVEILDE DGEVVWSADL EEQADETDPE AGKYKDAVPT FHGLSRGGEV
     QGKLVYAHYG RKQDYDALVE QGVDLNGSVV ITRYGGIFRG LKVKGAQDLG AVACLIYSDP
     RDDGTVTEEN GYEPYPMGPA RNPTSVQRGS TQFLSIYPGD PTTPGYPSYE NSTRSEGSNI
     PSIPSLPISW ANAKVLLEEI ADGGKDRTIS LVNHVDDRVI PIWNTMGVIP GHIKDEVVVV
     GNHRDAWVMG ATDPSSGTAS IHEVVRGLGA LLKEGWTPLR TIVIASWDAE EYGLIGSTEW
     GEDFADWIDE HVVAYVNLDS SVGGSRFYSS SSPSLAHFMR GAAESIAHPT KPGLTLWDAT
     QDRGPLYGTH GRVDEEAVRV YEEEQAQLAA AAADELGVGV LGSGSDYTVF LQRIGVASTN
     NGFTSTLSDP VYHYHSVFDS QRWQELYADP GFLRHVAIAK FLGLQTLRLV DSIILPFNTT
     HYAVQLGAYL DHVEQIALAA SLDVDFSDLR ESIDSLYAAS QSLDEEKFKA EHEIKRFIRR
     IVRRRLIKRH LRRAWCTIKK VFGKPCAERR LNAVEGVHHQ LDEPRSNHVA PPFQKRDGRA
     FKPRVGLWGG KMWEREQHAR EHAHERSGGC QVQWRARARP NFDDKLRERF RQVVKRVRTV
     NKKLGSFERG FIHPDGIKDR EWYRHLGVAP GKWLGYGATT LPGLTEAITF EANATLVRYE
     AERLQELIDR LAEEILP
//