ID A0A1X6NHK8_9APHY Unreviewed; 1929 AA.
AC A0A1X6NHK8;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=POSPLADRAFT_1128861 {ECO:0000313|EMBL:OSX68101.1};
OS Postia placenta MAD-698-R-SB12.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Postiaceae; Postia.
OX NCBI_TaxID=670580 {ECO:0000313|EMBL:OSX68101.1, ECO:0000313|Proteomes:UP000194127};
RN [1] {ECO:0000313|EMBL:OSX68101.1, ECO:0000313|Proteomes:UP000194127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MAD-698-R-SB12 {ECO:0000313|EMBL:OSX68101.1,
RC ECO:0000313|Proteomes:UP000194127};
RG DOE Joint Genome Institute;
RA Gaskell J., Kersten P., Larrondo L.F., Canessa P., Martinez D., Hibbett D.,
RA Schmoll M., Kubicek C.P., Martinez A.T., Yadav J., Master E.,
RA Magnuson J.K., James T., Yaver D., Berka R., Labutti K., Lipzen A.,
RA Aerts A., Barry K., Henrissat B., Blanchette R., Grigoriev I., Cullen D.;
RT "Genome Sequence of the Model Brown-Rot Fungus Postia placenta SB12.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR EMBL; KZ110591; OSX68101.1; -; Genomic_DNA.
DR STRING; 670580.A0A1X6NHK8; -.
DR OrthoDB; 2909243at2759; -.
DR Proteomes; UP000194127; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039904; TRANK1.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR21529; MAMMARY TURMOR VIRUS RECEPTOR HOMOLOG 1, 2 MTVR1, 2; 1.
DR PANTHER; PTHR21529:SF4; TPR AND ANKYRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Helicase {ECO:0000256|PROSITE-ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000194127}.
FT DOMAIN 205..588
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT REGION 1903..1929
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 226..233
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1929 AA; 220575 MW; E9C5F3FFD6CD5B4C CRC64;
MKAALYFDSA EGFGQWRVLI STRADSHLRQ ARKKNRNLFD IIIKKIKELS SGHFSEDNQK
LLTGTETDVP IYEAKMTRDS RLVYQIDCVP EFESNVSILI VIKLFGIYTH AQLDQRFWDG
VGYQLGRKGK EYRKRCTFRN RPSKVGVHAG VILPAEFPPP QEATLESPSL EKYVTFSQVP
SFVTFVASTL TGDDRILADA DVAHVFDVSP LEKVIIEHQH SCYVLGRSGT GKTTTMLFKM
LGIERSYQLM QNETMHKPRQ MFVTQSRVLA EKVKDFFLKL HESLLSADKS PEEIRAIVAS
RQAQQEQGLV DLDEEIDWRG DLPKRYGDLT DEHFPMFITY DQLCRLLEAE LDNSPNSQST
KPFVQNIAEE TNGQHGLSND YMQQLRAAFV SYGVFLESYW PHFTQSLTKG LDPALVFAEF
MGVLKGSEQT LSSDGLSLNK DQYSNLSHRT QGTFVNQRET IYKLFQAYTK RKRDHSHYDA
ADRTHAILKR LRDGVPGQLV DFIYIDEAQD NLLIDALVIR TICNNPDAGL FWAGDTAQTI
SIGSAFRFDD LKAFLYRIEV DLLISVNSHG RSRLQPRTFQ LAVNYRSHAG IVNCAHSVIE
LITRFWPHAI DNLAPEKGII EGLKPVFFSG WDEDTARYEQ FLFGESGSQI EFGAQQCILV
RDDAARERLR AQVGDIGLIM TLYESKGLEF NDVLLYNFFA DSTVDLSQWR VILNALPEGR
NDKYKAPTFD DTRHNGVCRD LKFLYVAITR ARKNLWIADS SDKGNPMRIL WTMKDQIQNC
TPGSDVPQLA MSSTPEEWAK TALALFNNRR YSQAMHCYER ASMPREKAVA HAYFLREQAR
STSVNAQEHG SYREAAFRTA ADAFYECAES AVIEKKSYFR ISAECYSLSG DDGLAAAAYV
RASEYTLAAQ HYRKGAMFDE AVDLIRSHRD VVDTTIAESI IDVSRLEYLR ERKLKQAREL
FETDEEALEY MDDFGLDVAQ ATLLEELERF ADAAQLHLAE GRTLDAIKTL LRDTNTDSLQ
LACRYLLDGL WRGLPLGLTP RSESARANTT LTELIRMSAD FNVDALDERT RDELLMFRAI
IADDSATLLE LGERFYRWHA NGAAALRCLD HVFTGLPKLL VASALEVTSS LHQFLLYARL
LQGFLSKAYS CDNEDIQRLV GFEVATEDFF LVPRETYLFS RCNHHSTPSL RPTDQGALVL
RWEIERLFKQ ILRGRLHQKV VDENDLCRRL RSLQPCLAFV ASGHCSRLAT GECPLEHLPA
EAYNLELYNL RVRIVLQQIL IYHTIYSIEH PAELSRQRRY WLRRLHEMLN PPFYKVGSPA
SLRGLTIPEF NDAVHTIGSW LVDWLYSLDP YNPSGYAPNF LTSFIRVASL AFAFYPEVAR
LQIPRVRCVS AYRPEMLMRQ HASDATYVIH DLIKFMENET QASLSRGILF TYHVLQKQVP
IDVVVLCNFL DFLCGLLVMC THFRYNTLHD VTLPKSWIIR LSGNLHKLKD RDTRLVHVYI
RPMAELLKQM YTGENADHLL YESRNLSTIT WRVRNMFVAR ICKNLCLLGY NSRLDWLRKD
ILAIVTSLRK HMRGSDPLLE RYISARLWDH LAREVRQNSA ANTSLDEMIQ IHEASRTSGQ
LPTFPNVRHI VYNTIDEIPI LLASGATSLP KAELRRDATP FPQSHEANET QVNGMMIPAV
STAPSPDDVY TAGDEDIDTE DVGAEDMKPE EEFDGADVVI SAEDSQMNAV SMQPSEQELK
AALTLLTVYR AYVLRRTRRE QERSMKAIHA LRRRVIASFH IASKDMEWPH RYYRMLFLGP
IPHAVICLEL LHAHLAEAKS SAKKRLNIAI HHDLEAVKAG LTEIVQLVKG SQRLKEALKP
DADLHKRRDI EQLKKYVVEV RELARRMSTK DWQDDMELAY KGIVEPRQPP AKKPKPELNV
DDEIDDEYM
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