ID A0A1X6WKH1_9ENTE Unreviewed; 560 AA.
AC A0A1X6WKH1;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=PTS system, mannitol-specific IIB component / PTS system, mannitol-specific IIC component {ECO:0000313|EMBL:SLM84740.1};
DE EC=2.7.1.191 {ECO:0000313|EMBL:SLM84740.1};
GN ORFNames=FM121_01510 {ECO:0000313|EMBL:SLM84740.1};
OS Vagococcus fluvialis bH819.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Vagococcus.
OX NCBI_TaxID=1255619 {ECO:0000313|EMBL:SLM84740.1, ECO:0000313|Proteomes:UP000195918};
RN [1] {ECO:0000313|Proteomes:UP000195918}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bH819 {ECO:0000313|Proteomes:UP000195918};
RA Dridi B.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FWFD01000003; SLM84740.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X6WKH1; -.
DR OrthoDB; 9814222at2; -.
DR Proteomes; UP000195918; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR036095; PTS_EIIB-like_sf.
DR InterPro; IPR003501; PTS_EIIB_2/3.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR013014; PTS_EIIC_2.
DR Pfam; PF02378; PTS_EIIC; 1.
DR Pfam; PF02302; PTS_IIB; 1.
DR SUPFAM; SSF52794; PTS system IIB component-like; 1.
DR PROSITE; PS51104; PTS_EIIC_TYPE_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Reference proteome {ECO:0000313|Proteomes:UP000195918};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SLM84740.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 48..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..347
FT /note="PTS EIIC type-2"
FT /evidence="ECO:0000259|PROSITE:PS51104"
SQ SEQUENCE 560 AA; 62783 MW; 2B638333D66C865F CRC64;
MKMKQKIGSF RKFGHFLSSM MMPNLSIFIA WGIINTFSKF TDGQVQELLV STEEFLINIL
LPLLIAYFGG RKIEKIRGGT VSAIAVIGLI IGADSPQIVG AMLIGPLAAY SYHRINQFLE
TKIKEGYQML LHNLLVGMIG SFFCLLGIFL FVPIINGINE GLSLSASWMI EHQLVPFVSL
LIDPLKILFF NNAINHGVLT PLGLNMVSSN GQSILFLLET NPGPGLGILL AYAVKGNSLN
KKNARTAFFI QLFGGIHEVY FPFVLMEPLL FVVVALSGFT GTFIFELFQV GLRYPVSPGS
VFLILASTSS GSLLGVCLGI LVSFILSFTL ASIILKRRYL ENETEKNQVE EPIKMTQFPL
KVNKIIVACD AGIGSSAMGA SLLRRNSQEK YGVIKIENQS VYDVVNNQTS LVLVHPQLEK
ILLENAPDVQ VLLIENFLEI NDMVTLLQNY PLEEIKQEKG LISQKENQLL EIVILFEKNI
RGSQTMAIEM MRKKLDQQEL NYTITKQAIE TLVINKNCWY ILTKEMEERQ QLKLKTSFIL
EMASLFNMKE FEKWLQKVGE
//
