ID   A0A1X6WXQ9_9MICO        Unreviewed;       518 AA.
AC   A0A1X6WXQ9;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Sodium/alanine symporter family protein {ECO:0000313|EMBL:SLM90505.1};
GN   ORFNames=FM110_05045 {ECO:0000313|EMBL:SLM90505.1};
OS   Brachybacterium nesterenkovii.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC   Brachybacterium.
OX   NCBI_TaxID=47847 {ECO:0000313|EMBL:SLM90505.1, ECO:0000313|Proteomes:UP000195981};
RN   [1] {ECO:0000313|EMBL:SLM90505.1, ECO:0000313|Proteomes:UP000195981}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIP104813 {ECO:0000313|EMBL:SLM90505.1,
RC   ECO:0000313|Proteomes:UP000195981};
RA   Peterson S.W.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
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DR   EMBL; FWFG01000048; SLM90505.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X6WXQ9; -.
DR   Proteomes; UP000195981; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF7; SODIUM_PROTON-DEPENDENT ALANINE CARRIER PROTEIN YRBD-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Reference proteome {ECO:0000313|Proteomes:UP000195981};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        68..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        146..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        187..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        212..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        241..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        303..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        369..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        409..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        433..454
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   518 AA;  55510 MW;  270FCA6116A3E080 CRC64;
     MIQNLIDGAN GLIWSLPLVL LCLLAGLYFS LRTVFLQVRC IPDMLAQLRD GEASQDGTSS
     FQSLMMSLAG RVGMGNIGGV ATAIAIGGPG AVFWMWTVAF LGAATSFIEC TLGQIYKEKD
     VDTGEYRGGP AYYIEKAYKH TAAGPLFLVY AIVFAVVTIF AMCYFLPGVQ ANGIASSMFA
     AWNLPHWITA VALVIVLAFI VIGGVKRIAT FAVMVVPVMA VLYIIAALIV FLINVDQIPH
     VFGMIFSSAF GAHAVFGAIV GKAVEMGVKR GLYSNEAGQG TGPHAAAAAE VSHPAKQGFA
     QAFAVYIDTL FVCTATAFLI ISTDMYRVYG PEGDTGPTIY EGKVPADVDY GPEFAQFGFD
     TVFSGMGPTF VAIALLFFAF TTIVAYYYMA EVNLAYLSRW IPNRTARRVV LHLLQALVLI
     SVVNGAVTTT GAAWALGDIG VGAMAWLNIV AILIMQGPAL KAFKDYQRQK KEGLDPQFDP
     RPLGIRNADF WEHRADGLVR QGQSGAELDD ITGGSSRS
//