ID   A0A1X6XQP4_9MICO        Unreviewed;       497 AA.
AC   A0A1X6XQP4;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Cardiolipin synthetase {ECO:0000313|EMBL:SLN00887.1};
DE            EC=2.7.8.- {ECO:0000313|EMBL:SLN00887.1};
GN   ORFNames=FM105_13750 {ECO:0000313|EMBL:SLN00887.1};
OS   Brevibacterium yomogidense.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Brevibacteriaceae;
OC   Brevibacterium.
OX   NCBI_TaxID=946573 {ECO:0000313|EMBL:SLN00887.1, ECO:0000313|Proteomes:UP000196581};
RN   [1] {ECO:0000313|EMBL:SLN00887.1, ECO:0000313|Proteomes:UP000196581}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B Co 03.10 {ECO:0000313|EMBL:SLN00887.1,
RC   ECO:0000313|Proteomes:UP000196581};
RA   Peterson S.W.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FWFF01000020; SLN00887.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X6XQP4; -.
DR   Proteomes; UP000196581; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008808; F:cardiolipin synthase activity; IEA:InterPro.
DR   GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR   InterPro; IPR022924; Cardiolipin_synthase.
DR   InterPro; IPR025202; PLD-like_dom.
DR   InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR   NCBIfam; TIGR04265; bac_cardiolipin; 1.
DR   PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR   PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR   Pfam; PF13091; PLDc_2; 2.
DR   SMART; SM00155; PLDc; 2.
DR   SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR   PROSITE; PS50035; PLD; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SLN00887.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        45..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          227..254
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
FT   DOMAIN          409..436
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
SQ   SEQUENCE   497 AA;  56347 MW;  D00E3EBCE49FE30F CRC64;
     MDPSGILVWI QSVFPAWIAV ALLVIDFCVR VVALGTIPYR RKPSVALGWL ILIFMIPFGG
     ILVFLVFGSP KLPVRRREKQ HEINQRVKAA TGHQAIIGTS DHLIEPLSTA AQLNYELGAL
     PMVHGNDFEL ITDSVHCMER MTEQIETAQH YIHFEFYIVA LDDTTRPLLD SLIAAHRRGV
     AVRVLIDHVG SIGYPGYRKL VRTLDDAGLM WRRSLPIRPW RGEYQRPDLR NHRKILVVDG
     QTAFTGSQNV IHPSYNKRKN VKRGLMWKDL MVRCTGPIVD ELDAVFASDW YSETDDALLG
     EFDEELDAPP DSTGIMAQVV PSGPGFEQEN NLQLFTHIIY NANRSVVISS PYFVPDNALL
     TALKTESQSG VDVRLYVGAT SDHWITGKAQ ESYYDELVEA GVTIYQYHSP TVLHSKFILV
     DDEVTVIGSS NMDERSFAMN HEVSLFIVDE EFTQRMYALE RDDYQLHSVP LDAETWRSRS
     WVRKYVENVC RLGSSLL
//