ID A0A1X6YJ02_9RHOB Unreviewed; 217 AA.
AC A0A1X6YJ02;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Precorrin-8X methylmutase {ECO:0000313|EMBL:SLN22579.1};
DE EC=5.4.99.61 {ECO:0000313|EMBL:SLN22579.1};
GN Name=cobH {ECO:0000313|EMBL:SLN22579.1};
GN ORFNames=ROA7450_00860 {ECO:0000313|EMBL:SLN22579.1};
OS Roseovarius albus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseovarius.
OX NCBI_TaxID=1247867 {ECO:0000313|EMBL:SLN22579.1, ECO:0000313|Proteomes:UP000193061};
RN [1] {ECO:0000313|EMBL:SLN22579.1, ECO:0000313|Proteomes:UP000193061}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7450 {ECO:0000313|EMBL:SLN22579.1,
RC ECO:0000313|Proteomes:UP000193061};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
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DR EMBL; FWFX01000002; SLN22579.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X6YJ02; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000193061; Unassembled WGS sequence.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:UniProtKB-EC.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:SLN22579.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000193061}.
FT DOMAIN 16..209
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 217 AA; 22801 MW; 76ADA4FE7B3E192B CRC64;
MTLDMMRPYE KDPSAIYAES FATVRREARL DRFGPGLEAL AIRLIHACGM VEVADWLDFS
PDVYESGHAA LQAGAPVLCD CEMVGAGIIR RYLPADNQVI VTLNDPSVPG RAKDIGNTRS
AAAVELWAEH LEGAVVAIGN APTALFHLLE LLDQGAPKPA AILGFPVGFV GASESKAELA
ARPRGCEFVA LRGRRGGSAI ASAAVNALAA GLPEIAK
//
