ID   A0A1X6ZRT2_9RHOB        Unreviewed;       789 AA.
AC   A0A1X6ZRT2;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Aminomethyltransferase {ECO:0000313|EMBL:SLN59401.1};
DE            EC=2.1.2.10 {ECO:0000313|EMBL:SLN59401.1};
GN   Name=gcvT_7 {ECO:0000313|EMBL:SLN59401.1};
GN   ORFNames=ROA7450_03073 {ECO:0000313|EMBL:SLN59401.1};
OS   Roseovarius albus.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Roseovarius.
OX   NCBI_TaxID=1247867 {ECO:0000313|EMBL:SLN59401.1, ECO:0000313|Proteomes:UP000193061};
RN   [1] {ECO:0000313|EMBL:SLN59401.1, ECO:0000313|Proteomes:UP000193061}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 7450 {ECO:0000313|EMBL:SLN59401.1,
RC   ECO:0000313|Proteomes:UP000193061};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FWFX01000010; SLN59401.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X6ZRT2; -.
DR   OrthoDB; 9772660at2; -.
DR   Proteomes; UP000193061; Unassembled WGS sequence.
DR   GO; GO:0004047; F:aminomethyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   InterPro; IPR018959; DUF1989.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF09347; DUF1989; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:SLN59401.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193061};
KW   Transferase {ECO:0000313|EMBL:SLN59401.1}.
FT   DOMAIN          194..361
FT                   /note="DUF1989"
FT                   /evidence="ECO:0000259|Pfam:PF09347"
FT   DOMAIN          425..674
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          700..781
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   789 AA;  86675 MW;  4A948FB1A98C912F CRC64;
     MLVSNYPEVI PGPPKPSVIV EPTVFSLPPG TERYVVEGAS AILIRLEPGD HLEIENTEGG
     QPCEIICASP DGRFDAGLIG AVDGGEAVGL QALLSSNDPS LHGLQLGIKA RGLDLSKAKA
     VKLYDAETPA RTTQTFVAQN ECHAIIAAPS DVMDFELQNT ATPLTAYVRR AVIKGHQKFS
     LPDPLAEPLQ SIRVHSATAE SFFVKAGDYI QIQDLDGRQC TDFQCFSARK LDRGIAYPLD
     VTTTRTVLHH NYAMPGLHAK YYDQDMTPLV EVIQDTCGRH DSFALACTAK YYDDIGYPGH
     VNCSENFNSA LAEHGVTPRP GWMAANFFFN TALDEHGVLT SDEPWSRPGD YVLLRALTDL
     VCVSSACPDD TSAANGWNPT DIHVRVYSGA ETFQRSIAYR PTPNAESKMT KETGFHDRFA
     QFTENFIEYN GFWLANCTSI AGPIEEYHAC RQKCVVLDLS ALRKFEITGP DSEALCQYVF
     TRNMKTLPVG GVVYTAMCYE HGGMIDDGTV FRLGKDNFRW IGGSDYSGDW IREKAEDLGL
     KVLVRCSTDM QHNIAVQGPE SRNLLKKVIW TAPHQPNFED LEWFRFTPAR IGHDQGVPVV
     VSRTGYTGEL GYEIFCHPKH AGAVFDAVWD AGQEHGIRPM GLEALDMVRI EAGLIFAGYD
     FSDQTDPFEA GIGFTVPLKS KTDDFIGRAA LIRRKETPAR KLVGLDIESA VDVAHGDCVH
     IGRAQIGEVT SSMRSPLLGK NIALARVDVT HHAVGTKVEI GKLDGQQKRL PATVVPLSHY
     DPQKTRPRS
//