ID A0A1X6ZSH9_9RHOB Unreviewed; 529 AA.
AC A0A1X6ZSH9;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Alcohol dehydrogenase [acceptor] {ECO:0000313|EMBL:SLN59494.1};
DE EC=1.1.99.- {ECO:0000313|EMBL:SLN59494.1};
GN Name=alkJ {ECO:0000313|EMBL:SLN59494.1};
GN ORFNames=ROA7450_03079 {ECO:0000313|EMBL:SLN59494.1};
OS Roseovarius albus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseovarius.
OX NCBI_TaxID=1247867 {ECO:0000313|EMBL:SLN59494.1, ECO:0000313|Proteomes:UP000193061};
RN [1] {ECO:0000313|EMBL:SLN59494.1, ECO:0000313|Proteomes:UP000193061}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7450 {ECO:0000313|EMBL:SLN59494.1,
RC ECO:0000313|Proteomes:UP000193061};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
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DR EMBL; FWFX01000010; SLN59494.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X6ZSH9; -.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000193061; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00623; GMC_OXRED_1; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU003968};
KW Oxidoreductase {ECO:0000313|EMBL:SLN59494.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000193061}.
FT DOMAIN 80..103
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00623"
FT DOMAIN 253..267
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 82
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 217
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 529 AA; 57906 MW; 1BBCD5B0F493F061 CRC64;
MEADFIIIGA GSAGCVLANR LSKNPNNRVV LLEAGGKDTN PWIHIPVGYF KTIHNPTVDW
CYETEPDPGL NGRSIEWPRG KVLGGSSSLN GLLYVRGQPQ DYDRWRQMGN EGWAWDDVLP
LFKRSEKNER GADEYHGDQG GLSVSNMRIQ RPITDAWVAA AQAAGYKFNP DYNGADQEGV
GFFQLTSRNG RRCSSAVAFL NPAKSRENLQ IITNAHVQRI DIEDKCATGV TFKDRSGTLQ
TIKANREVIL SAGAINSPQI LMLSGIGEAA QLNEHGIDII ADLPGVGKNL QDHLQARLVY
KCNEPTLNDE VSSLFGQAKI GLKYLMFRAG PMTMAASLAT GFMKTRDELE TPDIQFHVQP
LSAENPGKGA DKFSAFTMSV CQLRPESRGE IRLTSADPKV YPKIIPKYLS TETDCRTIVE
GINIARRIAR HAPISSKISE EFRPNANLDI EDYEATLDWA RSNTASIYHP TGTCKMGSGA
DAVVDHHLKV HGIKGLRVAD CSIMPEIVSG NTNAPAIMIG EKASDLVLK
//
