ID   A0A1X7A8K6_9RHOB        Unreviewed;       384 AA.
AC   A0A1X7A8K6;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Dimethylsulfonioproprionate demethylase DmdA {ECO:0000313|EMBL:SLN73062.1};
DE            EC=2.1.1.269 {ECO:0000313|EMBL:SLN73062.1};
GN   Name=dmdA_2 {ECO:0000313|EMBL:SLN73062.1};
GN   ORFNames=ROA7450_04088 {ECO:0000313|EMBL:SLN73062.1};
OS   Roseovarius albus.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Roseovarius.
OX   NCBI_TaxID=1247867 {ECO:0000313|EMBL:SLN73062.1, ECO:0000313|Proteomes:UP000193061};
RN   [1] {ECO:0000313|EMBL:SLN73062.1, ECO:0000313|Proteomes:UP000193061}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 7450 {ECO:0000313|EMBL:SLN73062.1,
RC   ECO:0000313|Proteomes:UP000193061};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FWFX01000021; SLN73062.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X7A8K6; -.
DR   OrthoDB; 9772660at2; -.
DR   Proteomes; UP000193061; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   PIRSF; PIRSF006487; GcvT; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:SLN73062.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193061};
KW   Transferase {ECO:0000313|EMBL:SLN73062.1}.
FT   DOMAIN          37..268
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          295..375
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   384 AA;  42393 MW;  D6FC7CF7BCDE6957 CRC64;
     MSHELDFAQF SFGTQVRKSP YSDAALRWGA KGFSVYNHMY IPRDFGDPGQ NFWNLVNEAI
     LCDVSVERQV EIKGPDAAKF TQFLSCRDLS KCEVGQCKYV LITDQSGGII NDPILLKLAE
     DHFWLSIADS DVLLWARGIA VNSGMDVEIS EPDVSPLQLQ GPKSREVLRA AFGDTPTELK
     YYRFMEFDWE GVPLIISRTG WSSELGYEVF LRDGSAGDRL WEHLMAVGTP LGLKPGHTSS
     IRRIEAGMLS YHADMTLANN PYELGMGRLV DLDMEADFVS KAALTKIKDT GVSQQLVGLE
     IDGDPFIGSN DFFWPIMKDG VQVGTVTSAI YSPRLEKNIA LAMISINHAA SGGALQVDKL
     SETRTCTVVP IPFYDPKKSL ASAS
//