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Database: UniProt
Entry: A0A1X7AJE0_9GAMM
LinkDB: A0A1X7AJE0_9GAMM
Original site: A0A1X7AJE0_9GAMM 
ID   A0A1X7AJE0_9GAMM        Unreviewed;       617 AA.
AC   A0A1X7AJE0;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   16-JAN-2019, entry version 13.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:SMA46502.1};
GN   ORFNames=EHSB41UT_02182 {ECO:0000313|EMBL:SMA46502.1};
OS   Parendozoicomonas haliclonae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Endozoicomonadaceae; Parendozoicomonas.
OX   NCBI_TaxID=1960125 {ECO:0000313|EMBL:SMA46502.1, ECO:0000313|Proteomes:UP000196573};
RN   [1] {ECO:0000313|EMBL:SMA46502.1, ECO:0000313|Proteomes:UP000196573}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SB41UT1 {ECO:0000313|EMBL:SMA46502.1};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; FWPT01000004; SMA46502.1; -; Genomic_DNA.
DR   Proteomes; UP000196573; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000196573};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000196573}.
FT   DOMAIN      314    505       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      525    594       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     322    329       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   617 AA;  68728 MW;  443DD8210407EB9A CRC64;
     MPRELWQKCM EILQDELPIQ QFNTWLRPLK VMADQDELCL LAPNRFVLDW VKDKYLPRIE
     EIFMDLSDGN PPAIALGVSN RRPSFGMRMS GSRSSATSSR SSSPSSSGFS SGSSGFSSRF
     QEQPKRSHDE DNGQAILDLY SQPQGSSAPS RNESTASSGY GQPARQESSS ASDATVVAEL
     EKELTGVANE TETVLTPAAV RQRFVNPLRS SQGEDRNYQP KAEVNVAGDN PSIEVTPLSS
     QPPSSQIEYN EPTIITPPAP KVVIPKQRPV EVEGSIKHTS SLNRTFVFDT FVEGKSNQLA
     LAAAKQVAEN PGSAYNPLFL YGGVGLGKTH LMHAVGNQLA KQNPDAKIIY LHSERFVADM
     VKALQLNAIN DFKRYYRSVD ALLIDDIQFF AGKERSQEEF FHTFNALLEG GQQMILTCDR
     YPKEIAGLEE RLKSRFGWGL TVAVEPPELE TRVAILMKKA EQAKIDLPHE SAFFIAQRIR
     SNVRELEGAL KRVIASAHFM GRKIDVDLIR ESLKDLLALQ DKQVSIENIQ RTVAEYYKIK
     ISDILSKRRS RSVARPRQIA MALSKELTNH SLPEIGDAYG GRDHTTVLHA CRKVKQLCET
     DAEIAEDHKN LLRLLTS
//
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