ID A0A1X7CAU0_9ACTN Unreviewed; 706 AA.
AC A0A1X7CAU0;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein {ECO:0000313|EMBL:SME93122.1};
GN ORFNames=SAMN02745830_00561 {ECO:0000313|EMBL:SME93122.1};
OS Streptomyces sp. Amel2xC10.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1305826 {ECO:0000313|EMBL:SME93122.1, ECO:0000313|Proteomes:UP000192930};
RN [1] {ECO:0000313|EMBL:SME93122.1, ECO:0000313|Proteomes:UP000192930}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Amel2xC10 {ECO:0000313|EMBL:SME93122.1,
RC ECO:0000313|Proteomes:UP000192930};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FWZW01000001; SME93122.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X7CAU0; -.
DR Proteomes; UP000192930; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR022514; NHPM_micro_ABC1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005074; Peptidase_C39.
DR InterPro; IPR039421; Type_1_exporter.
DR NCBIfam; TIGR03796; NHLM_micro_ABC1; 1.
DR PANTHER; PTHR24221:SF658; ABC TRANSPORTER B FAMILY MEMBER 29, CHLOROPLASTIC; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF03412; Peptidase_C39; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS50990; PEPTIDASE_C39; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:SME93122.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000192930};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 155..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..123
FT /note="Peptidase C39"
FT /evidence="ECO:0000259|PROSITE:PS50990"
FT DOMAIN 155..435
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 472..705
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 706 AA; 75782 MW; 9B2D926BCB17DC50 CRC64;
MEAVECGAAS LAMVLAHHGR HVPLEELRIA CGVSRDGSRA GNLLKAARSY GLTAKGMQMD
LAALAAVRSP AILFWEFNHY VVYDGMGRRF GRRGVFVNDP GKGRRFVPME DFDGSFTGVV
LVLEPGAGFE RGGRRPGALG ALPARLRGTA GTLPAAVLAS LLLVVVGAAV PALSRTWIDT
YLIGGQTSLL GTLFAAMGAC VLLSLVLTWL QQANLHHGRI VSSTLSSARF LRHLLRLPVT
FFSQRSPADL VQRLQSNDAV AETLARDLAA AGVDAVVVVL YAVLLYTYDP QLTFVGVGVA
LLNVVAMRVV VRMRAMRTAK LRADSARLTN TAYTGLQLIE TMKATGGEDA YFRKWAGQHA
TTLEEQQRLG VPSAWLGVVA PTLASLNSAL ILWIGGVRAI EGGISVGLLV AFQALVTRFT
APLTRLNGVA GRIQDFAADV ARLKDVENFR ADPLYDRPAG ADGSTRRLRG LVELVDVTFG
YSPLDKPLLS GFDLTVGPGQ QVALVGGSGS GKSTVSRLIS GLYAPWEGVI RIDGRRLDDI
PRGALAASVS FVDQEVFLFE GTVRDNVALW DPSVPDEAVV AALRDAALYD VVARRPGGIH
SRVEQDGRNF SGGQRQRLEI ARALVRRPSI LVLDEVTSAL DAETERVVMD NLRRRGCACV
VIAHRLSTVR DSDEIVVLQH GTVVERGRHD DLVARGGAYA ALVRER
//
