ID   A0A1X7EAN4_9ACTN        Unreviewed;       266 AA.
AC   A0A1X7EAN4;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Protein-disulfide isomerase {ECO:0000313|EMBL:SMF30580.1};
GN   ORFNames=SAMN02745830_02763 {ECO:0000313|EMBL:SMF30580.1};
OS   Streptomyces sp. Amel2xC10.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1305826 {ECO:0000313|EMBL:SMF30580.1, ECO:0000313|Proteomes:UP000192930};
RN   [1] {ECO:0000313|EMBL:SMF30580.1, ECO:0000313|Proteomes:UP000192930}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Amel2xC10 {ECO:0000313|EMBL:SMF30580.1,
RC   ECO:0000313|Proteomes:UP000192930};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FWZW01000005; SMF30580.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X7EAN4; -.
DR   OrthoDB; 4135024at2; -.
DR   Proteomes; UP000192930; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR012336; Thioredoxin-like_fold.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   Pfam; PF13462; Thioredoxin_4; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000313|EMBL:SMF30580.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192930};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        34..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          81..261
FT                   /note="Thioredoxin-like fold"
FT                   /evidence="ECO:0000259|Pfam:PF13462"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..24
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   266 AA;  28330 MW;  A42F8A485154DF39 CRC64;
     MSKRNTQAAK TAARERLRLE RERQAKRAKA KRQIIVAASA VAVLAAAGGI GYAIVQANKP
     GYWDEAAKAT VVAPANTSGK NGTTVVIGES KSDNLVHLYE DPRCPGCANF EQTIGEAVNK
     GMEGDDYKLS FTIGTFLDDR LGGEGSKNAL SALGAALNVS PEAFLDYKAA LYSTEYHPAE
     STDEFAKDAY LIKVANTVDA LKNNKKFQDA VEKGTYDAWA TRMSESFQEA EGVSSTPTIK
     INDKVVATPA DAAGWAKALK DAGVTK
//