ID A0A1X7EVJ9_9ACTN Unreviewed; 574 AA.
AC A0A1X7EVJ9;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase {ECO:0000313|EMBL:SMF40388.1};
GN ORFNames=SAMN02745830_03333 {ECO:0000313|EMBL:SMF40388.1};
OS Streptomyces sp. Amel2xC10.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1305826 {ECO:0000313|EMBL:SMF40388.1, ECO:0000313|Proteomes:UP000192930};
RN [1] {ECO:0000313|EMBL:SMF40388.1, ECO:0000313|Proteomes:UP000192930}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Amel2xC10 {ECO:0000313|EMBL:SMF40388.1,
RC ECO:0000313|Proteomes:UP000192930};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FWZW01000006; SMF40388.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X7EVJ9; -.
DR Proteomes; UP000192930; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF56; OXYGEN SENSOR HISTIDINE KINASE RESPONSE REGULATOR DOST; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SMF40388.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000192930};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 484..574
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 574 AA; 61062 MW; 527444A58D724D1A CRC64;
MAESPAQGRK GRPAAPQLRL DELLEGLQAQ IEHVRATRDR VHTLLDAVLA IGSDLDLDVV
LRRITESAVT LVDAQYGALG VLGDEGKIRQ FITVGMDEET VHGIDHYPEG HGILGLLIRK
PEPLRLPELG SHPDSVGFPA GHPPMTTFLG APVRVRDQVF GNLYLTDKRD GAEFDDDDEA
VLRTLAAAAG VAIDNARLYE DARRREKWLA ASSELTRSLL SGADPDRVLH QVAATVRSLS
GAALVTLAVP FEGGDELVIE AADGEGAEQV HGLVLPAPTL AAKVFTSNQQ ITSGALSDEP
QGGGGSAAQI ALGPGFLLPL GSAEHVRGVL QVANLPGGDA FTDAAMAMIT GFADQAALAL
EIAEHRREAD HLMVLTDRDR IARDLHDLAI QRLFASGLTL NSVLGRVSDR PQVAERVQRV
VEDLDDTIKT IRGTIYALHE RDRTDGRGGL RAKVLAETDR AAAALGFTPA LRMTGLLDTA
VPPGHAEHLL AVLREALSNA ARHAHATGVE VTVETDGSRL RLRVADNGTG IDPAVTRRSG
LDNLRRRATE LDGSLTLTSN APTGTVVEWS VPLT
//
