ID A0A1X7G4U5_9ACTN Unreviewed; 1167 AA.
AC A0A1X7G4U5;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=ATP-binding cassette, subfamily C, CydCD {ECO:0000313|EMBL:SMF63996.1};
GN ORFNames=SAMN02745830_04958 {ECO:0000313|EMBL:SMF63996.1};
OS Streptomyces sp. Amel2xC10.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1305826 {ECO:0000313|EMBL:SMF63996.1, ECO:0000313|Proteomes:UP000192930};
RN [1] {ECO:0000313|EMBL:SMF63996.1, ECO:0000313|Proteomes:UP000192930}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Amel2xC10 {ECO:0000313|EMBL:SMF63996.1,
RC ECO:0000313|Proteomes:UP000192930};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FWZW01000011; SMF63996.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X7G4U5; -.
DR OrthoDB; 9806127at2; -.
DR Proteomes; UP000192930; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR GO; GO:0042883; P:cysteine transport; IEA:InterPro.
DR GO; GO:0034775; P:glutathione transmembrane transport; IEA:InterPro.
DR CDD; cd18584; ABC_6TM_AarD_CydD; 1.
DR CDD; cd03228; ABCC_MRP_Like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR014223; ABC_CydC/D.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR014216; ABC_transptr_CydD.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR NCBIfam; TIGR02868; CydC; 1.
DR NCBIfam; TIGR02857; CydD; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR PANTHER; PTHR24221:SF261; ATP-BINDING_PERMEASE PROTEIN CYDD; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:SMF63996.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000192930};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 603..626
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 638..657
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 718..740
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 746..767
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 830..852
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 858..882
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..306
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 335..570
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 604..887
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 921..1156
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 547..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1167 AA; 122155 MW; F250A812996ECA07 CRC64;
MFHVKPIDPR LLRYARATRL FLLAVVGLGA VGAGLVIAQA MLIAEAVVGA FQHGMSVSEL
RTPLLLLVAV AIGRAVVSWL TELAAHRASA AVKSELRGRL LERAAELGPG WLSGQRTGSL
VALATRGVDA LDDYFSRYLP QLGLAVVVPV AVLARIVTED WVSAAIIVCT LPLIPVFMVL
IGWATQSRMD RQWRLLSRLS GHFLDVVAGL PTLKVFGRAK AQAESIRSIT GEYRRATMRT
LRIAFLSSFA LELLATLSVA LVAVTIGMRL VHGDMDLYIG LVILVLAPEA YLPLRQVGTQ
YHAAAEGLAA AEEIFAVLET PVPAPGTTRV PEGPLAFEGV TVRYPGRSAD AVSDVSFTVE
PGETVALVGP SGVGKSTLLH TLLGFVPPTE GRVRAGGVDL TVADLEQWRS RIAWVPQRPH
LYAGTIADNV RLARPDADEG AVRRALADAG ALEFVDALPA GLGTVLGEDG AGLSAGQRQR
LALARAFLAD RPVLLLDEPT AALDGETEAE VVEAVRRLAA GRTVLLVVHR PALLAVADRV
VRLAETAPPR PAETAPRTAP AAPETAAAPA AADPEAFEEP AGAGAGGVLA RVRALAGARR
GRLALALLLG SLALGSAVGL MATSGWLISR ASQQPPVLYL MVAVTATRAF GIGRAVFRYG
ERLVSHDAVL RMLADTRVAV FRRLERLAPA GLRGTRRGDL LSRLVADVDT LQDYWLRWLL
PAGAAVAVSA GSVAFTAWLL PEAGAVLAAG LLTAGLGVPL VTGAVAHRAE RRLAPARGVL
ATRTADLLTG TAELTVSGAL PARAAEVRAA DGVLTRIASR AATATALGDG LTALVSGLTV
AASALVGAQA VAAGRLSGVT MAVVVLTPLA AFEAVLGLPL AVRHRRRVQR SAERIFEVLD
SPEPVREPER PGRPPAAPFP LVVEGMTARH AGQDRDALTG VDLTLTQGRR IAVVGPSGSG
KTTLAQVLLR FLDADSGTYT LGGTDADALD GDDVRRLVGL CAQDAHLFDS SVRENLLLAK
KDASEGEVRD ALSRARLLEW ADSLPEGLDT LVGEHGARLS GGQRQRLALA RALLADFPVL
VLDEPAEHLD LPTADALTAD LLAATEGRTT VLITHRLAGL DAVDEVVVLD AGRIVQRGPF
AELASVDGPL RSMVEREAAT ELLVAAG
//
