ID A0A1X7GBQ8_9BACL Unreviewed; 385 AA.
AC A0A1X7GBQ8;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN ORFNames=SAMN05661091_0300 {ECO:0000313|EMBL:SMF66876.1};
OS Paenibacillus uliginis N3/975.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1313296 {ECO:0000313|EMBL:SMF66876.1, ECO:0000313|Proteomes:UP000192940};
RN [1] {ECO:0000313|EMBL:SMF66876.1, ECO:0000313|Proteomes:UP000192940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N3/975 {ECO:0000313|EMBL:SMF66876.1,
RC ECO:0000313|Proteomes:UP000192940};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
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DR EMBL; LT840184; SMF66876.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X7GBQ8; -.
DR STRING; 1313296.SAMN05661091_0300; -.
DR Proteomes; UP000192940; Chromosome i.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000192940}.
FT DOMAIN 26..364
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 385 AA; 43580 MW; A748FC12A8C331C2 CRC64;
MSKVKVMTIF GVRPEAIKMA PLILELQRHP EHIESVVCVT AQHRQMLDQV LDVFKIVPDY
DLDVMKDRQT LNEITIRVLE GLEPVLREAK PDIVLVHGDT LTTFLASYAA FLQKIQVGHV
EAGLRTWNKL SPYPEEMNRQ LTGVLSDIHF APTDWSADNL RKENKNESTI YVTGNTVTDV
FQYTVQPDYT HPVLDWASGK RLILMTAHRR ESQGEPHRNI FRAIKRIADE FEDIAIVYPV
HPSPAVKEPA HEILGSHPRI KLIDPLDVVD FHNIYAHTHL ILTDSGGMQE EAPSFGVPVL
VLRDTTERPE GIDAGTLELV GTHEEDVYGR TKALLTDKEL YESMSQAANP YGDGHASERI
VNAILHHFGV VSDRPEKFHR MFTKS
//
