ID A0A1X7HW04_9BURK Unreviewed; 577 AA.
AC A0A1X7HW04;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Chloride channel protein, CIC family {ECO:0000313|EMBL:SMG06166.1};
GN ORFNames=SAMN06265784_10156 {ECO:0000313|EMBL:SMG06166.1};
OS Paraburkholderia susongensis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=1515439 {ECO:0000313|EMBL:SMG06166.1, ECO:0000313|Proteomes:UP000193228};
RN [1] {ECO:0000313|Proteomes:UP000193228}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 29540 {ECO:0000313|Proteomes:UP000193228};
RA Varghese N., Submissions S.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FXAT01000001; SMG06166.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X7HW04; -.
DR STRING; 1515439.SAMN06265784_10156; -.
DR OrthoDB; 9767361at2; -.
DR Proteomes; UP000193228; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 453..509
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 577 AA; 62107 MW; 21B790BD4FF1C78A CRC64;
MLSFLLKLRT RAQHLFRLSE AHTMLVWSVV VGIAGAFATI VFREAIALLQ LAITGRSGSF
VEMARGLPWT MRIWLPAAGG LVAGCLLLIA QRHADKGSHT DYMEAVAIGD GVVPVRLSLW
RSVSSLFTIA SGGSIGREGP MVQLAALGAS LIGRWVHFDP SRLRLLVACG AAAGITSAYS
APIAGAFFVT EIVLGSIAME SFGPIVVSAV VANITMREFT SYKPPYEMPA FPTVAGPEVL
LFVALGALCG AAAPQFLRLL DVSKTGFRKL PMPLPLRLAL GGLVVGIIST WEPEVWGNGY
SVVNSILHSP WTWSALVLVL VCKLVATAAT AGSGAVGGVF TPTLFVGAAV GSLFGQGMHE
LWPHATSASY AYAMVGMGAF LAGATQAPLM AILMIFEMTL SYQVVLPLMV SCVVAYFIAR
AIGKTSMYEI TLRRNREEQE RSRLRATQMR ELIRPAQTVV PPNATVHDMT RVFLEYPVKY
LYVANEAGAF LGVVALKDIT SDLLDKRDTS TRTAADYLQP HFDVLTPDMS LGVALQHFMA
FQGERLPVIE SIAHPKLEGV VYKTSLLDAY FRMNPSP
//
