ID A0A1X7IBR1_9RHOB Unreviewed; 682 AA.
AC A0A1X7IBR1;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN02746000_00553 {ECO:0000313|EMBL:SMG12075.1};
OS Paracoccus sp. J56.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Paracoccus.
OX NCBI_TaxID=935850 {ECO:0000313|EMBL:SMG12075.1, ECO:0000313|Proteomes:UP000193912};
RN [1] {ECO:0000313|Proteomes:UP000193912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J56 {ECO:0000313|Proteomes:UP000193912};
RA Varghese N., Submissions S.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FXAQ01000003; SMG12075.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X7IBR1; -.
DR STRING; 935850.SAMN02746000_00553; -.
DR Proteomes; UP000193912; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:SMG12075.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000193912};
KW Transferase {ECO:0000313|EMBL:SMG12075.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 312..535
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 559..675
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 610
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 682 AA; 74830 MW; 6B6D61BBAC1CE246 CRC64;
MSSERTESLR SARIVLPFLT LPMVIGALWL AIYPHWREGG LVLISAGAVI MAWYLLAGIL
SARHIGRALI TKRDLDDVLP AIHQHEQPAM ATDAAGLILA QNQEALDRFG DLVGHRIHEV
LGRSHADPER MWSDLTIRLS RRGRIRADLG NGCEYTVTRR TRSEIRLWQA VACERSVTPP
PAVLGSDHGD FDSLPVALIV LDPTGNIIRA NAAARNLLGG QILGQKLSIL LDGLGREIGD
WVSDVCAGRT VGGSEVLHVK ADGPDRFVQL TLTRARGDYV TAVLSDASAL KTLEAQFVQS
QKMQAIGQLA GGIAHDFNNL LTAITGHCDL LMLRHDKADP DYADLDQISQ NANRAAALVR
QLLAFSRKQT LKPQIMDLRD TLSDLTHLLN RLVGERVVLT FDHDPALRMI RADRRQLEQV
IMNLVVNARD AMPDGGDINI STDNVRLETK AEFGRAILPA GDYVRVQVRD QGCGIAPDDL
VKIFEPFFTT KRVGESTGLG LSTAYGIVKQ TGGYIFCDSM LGEGSSFSLF FPAHDRHELE
KTSPPVVVPI RPLRELEATV LLVEDEAPVR SFASRALKLQ GFKVLEAACA EDALSLLADE
RLIVDVFVTD VVMPGMDGPA WVRTALRDRP DTKVIFMSGY TEDIFSEGRP PVPDAAFLAK
PFSLSDLTAL VTRQLGDQRR DE
//
